Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 3/20 | 0.35 |
| ▸ | HTR2C | P28335 | 3/20 | 0.35 |
| ▸ | DRD3 | P35462 | 3/20 | 0.35 |
| ▸ | HTR6 | P50406 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.34 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2569948 | 0.91 | MEN1 (0.36) | MEN1KMT2AHDAC1HDAC2DRD2 | |
| SCHEMBL2571305 | 0.90 | KDM4E (0.36) | KDM4EHDAC1HDAC2DRD2HTR2C | |
| SCHEMBL2569548 | 0.88 | AR (0.34) | MEN1KMT2AHDAC1HDAC2DRD2 | |
| SCHEMBL3023542 | 0.86 | F10 (0.45) | KDM4EMEN1KMT2AF10AR | |
| SCHEMBL2571214 | 0.85 | KDM4E (0.40) | KDM4EHDAC1HDAC2DRD2HTR2C | |
| SCHEMBL13070159 | 0.85 | F10 (0.39) | KDM4EKMT2ADRD2HTR2CDRD3 | |
| SCHEMBL2568969 | 0.84 | RAB9A (0.36) | MEN1KMT2AHDAC1HDAC2DRD2 | |
| SCHEMBL2571863 | 0.81 | RAB9A (0.34) | MEN1KMT2AHDAC1HDAC2DRD2 | |
| SCHEMBL2568110 | 0.81 | HDAC1 (0.34) | MEN1KMT2AHDAC1HDAC2DRD2 | |
| SCHEMBL2568026 | 0.80 | PSEN1 (0.33) | KDM4EHDAC1HDAC2DRD2HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1899330-B9 | SUBSTITUTED GLYCINAMIDES HAVING AN ANTITHROMBOTIC AND FACTOR XA-INHIBITING EFFECT | BOEHRINGER INGELHEIM INT (DE) | 2011-11-09 | — | — | EP | disclosed |
| EP-1899330-B1 | SUBSTITUTED GLYCINAMIDES HAVING AN ANTITHROMBOTIC AND FACTOR XA-INHIBITING EFFECT | BOEHRINGER INGELHEIM INT (DE) | 2010-11-24 | — | — | EP | disclosed |