Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FADS1 | O60427 | 1/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 6/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | LIPE | Q05469 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2566533 | 0.89 | FADS1 (0.44) | FADS1PIK3CDPIK3CBPIK3CGPIK3CA | |
| SCHEMBL2568025 | 0.86 | FADS1 (0.47) | FADS1PIK3CDPIK3CBPIK3CGPIK3CA | |
| SCHEMBL2562601 | 0.84 | FADS1 (0.51) | FADS1PIK3CDPIK3CBPIK3CGPIK3CA | |
| SCHEMBL2561473 | 0.84 | FADS1 (0.49) | FADS1PIK3CDPIK3CBPIK3CGPIK3CA | |
| SCHEMBL2995705 | 0.83 | FADS1 (0.39) | FADS1PIK3CDPIK3CBPIK3CGPIK3CA | |
| SCHEMBL2567552 | 0.83 | FADS1 (0.49) | FADS1PIK3CDPIK3CBPIK3CGPIK3CA | |
| SCHEMBL2566441 | 0.81 | FADS1 (0.47) | FADS1PIK3CDPIK3CBPIK3CGPIK3CA | |
| SCHEMBL2565109 | 0.81 | FADS1 (0.47) | FADS1PIK3CDPIK3CBPIK3CGPIK3CA | |
| SCHEMBL2567416 | 0.81 | FADS1 (0.47) | FADS1PIK3CDPIK3CBPIK3CGPIK3CA | |
| SCHEMBL2559985 | 0.81 | FADS1 (0.51) | FADS1PIK3CDPIK3CBPIK3CGPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2382218-A1 | DELTA-5-DESATURASE INHIBITORS | Takeda Pharmaceutical Company Limited (JP) | 2011-11-02 | — | — | EP | disclosed |
| WO-2010087467-A1 | DELTA-5-DESATURASE INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-08-05 | — | — | WO | disclosed |