Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CSF1R | P07333 | 4/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | AHR | P35869 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25666149 | 0.93 | CSF1R (0.44) | CSF1RKCNH2SCN5ATP53THRB | |
| SCHEMBL25666122 | 0.89 | KCNH2 (0.48) | RXFP1ALDH1A1KCNH2MAPTMAPK1 | |
| SCHEMBL25666121 | 0.89 | KMT2A (0.46) | RXFP1ALDH1A1CSF1RKCNH2MAPT | |
| SCHEMBL25666177 | 0.89 | CSF1R (0.42) | CSF1RKCNH2SCN5A | |
| SCHEMBL25666211 | 0.89 | KMT2A (0.48) | CSF1RKCNH2MAPTMAPK1TP53 | |
| SCHEMBL25666147 | 0.87 | KCNH2 (0.52) | CSF1RKCNH2MAPTHTTSCN5A | |
| SCHEMBL25666146 | 0.87 | KMT2A (0.46) | CSF1RKCNH2MAPTMAPK1TP53 | |
| SCHEMBL25666144 | 0.87 | RXFP1 (0.46) | RXFP1ALDH1A1KCNH2USP2 | |
| SCHEMBL25666151 | 0.85 | PDE4B (0.46) | CSF1RKCNH2 | |
| SCHEMBL25229097 | 0.82 | KMT2A (0.52) | CSF1RKCNH2MAPTMAPK1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023086220-A2 | PAPD5 INHIBITORS AND METHODS OF USE THEREOF | THE CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2023-05-19 | — | — | WO | disclosed |