Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 2/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | CCNC | P24863 | 1/20 | 0.45 |
| ▸ | CDK8 | P49336 | 1/20 | 0.45 |
| ▸ | CSF1R | P07333 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25666149 | 0.91 | CSF1R (0.44) | KCNH2CSF1R | |
| SCHEMBL25666208 | 0.90 | CCNC (0.45) | PDE4BKCNH2CCNCCDK8CSF1R | |
| SCHEMBL25666212 | 0.90 | MAPT (0.50) | PDE4BCSF1R | |
| SCHEMBL25666144 | 0.90 | RXFP1 (0.46) | PDE4BKCNH2 | |
| SCHEMBL25666147 | 0.89 | KCNH2 (0.52) | KCNH2CSF1R | |
| SCHEMBL25666146 | 0.87 | KMT2A (0.46) | KCNH2CSF1R | |
| SCHEMBL25666124 | 0.85 | RXFP1 (0.43) | KCNH2CSF1R | |
| SCHEMBL25666211 | 0.85 | KMT2A (0.48) | KCNH2CSF1R | |
| SCHEMBL25665052 | 0.83 | CNR2 (0.42) | PDE4BCSF1R | |
| SCHEMBL25665661 | 0.81 | PDE4B (0.46) | PDE4BCCNCCDK8CSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023086220-A2 | PAPD5 INHIBITORS AND METHODS OF USE THEREOF | THE CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2023-05-19 | — | — | WO | disclosed |