Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.80 |
| ▸ | MEN1 | O00255 | 2/20 | 0.80 |
| ▸ | MAPT | P10636 | 2/20 | 0.80 |
| ▸ | TP53 | P04637 | 1/20 | 0.80 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.80 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.80 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.80 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.80 |
| ▸ | HTT | P42858 | 4/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.77 |
| ▸ | LMNA | P02545 | 2/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.77 |
| ▸ | NPC1 | O15118 | 1/20 | 0.77 |
| ▸ | RAB9A | P51151 | 1/20 | 0.77 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.63 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.63 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.63 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.63 |
| ▸ | ACHE | P22303 | 2/20 | 0.63 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL257336 | 0.94 | KMT2A (0.69) | KMT2AMEN1MAPTTP53CYP1A2 | |
| Bromide SCHEMBL14656035 | 0.92 | KMT2A (0.67) | KMT2AMEN1MAPTTP53CYP1A2 | |
| SCHEMBL3212665 | 0.91 | KMT2A (0.95) | KMT2AMEN1MAPTTP53CYP1A2 | |
| SCHEMBL3205110 | 0.89 | KMT2A (1.00) | KMT2AMEN1MAPTTP53CYP1A2 | |
| SCHEMBL3196438 | 0.89 | KMT2A (1.00) | KMT2AMEN1MAPTTP53CYP1A2 | |
| Hydrochloric Acid SCHEMBL25217017 | 0.89 | KMT2A (0.91) | KMT2AMEN1MAPTTP53CYP1A2 | |
| SCHEMBL1108039 | 0.89 | KMT2A (1.00) | KMT2AMEN1MAPTTP53CYP1A2 | |
| SCHEMBL3215320 | 0.89 | KMT2A (1.00) | KMT2AMEN1MAPTTP53CYP1A2 | |
| SCHEMBL3212489 | 0.89 | KMT2A (1.00) | KMT2AMEN1MAPTTP53CYP1A2 | |
| SCHEMBL3212749 | 0.89 | KMT2A (1.00) | KMT2AMEN1MAPTTP53CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012028578-A1 | SUBSTITUTED FUSED PYRIMIDINONES AND DIHYDROPYRIMIDINONES | BAYER CROPSCIENCE AG (DE) | 2012-03-08 | — | — | WO | disclosed |