Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.69 |
| ▸ | MAPT | P10636 | 2/20 | 0.69 |
| ▸ | TP53 | P04637 | 1/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.69 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.69 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.69 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.69 |
| ▸ | HTT | P42858 | 4/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.67 |
| ▸ | NPC1 | O15118 | 1/20 | 0.67 |
| ▸ | RAB9A | P51151 | 1/20 | 0.67 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.54 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.54 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.54 |
| ▸ | ACHE | P22303 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL14656035 | 0.98 | KMT2A (0.67) | KMT2AMEN1MAPTTP53CYP1A2 | |
| SCHEMBL256682 | 0.94 | KMT2A (0.80) | KMT2AMEN1MAPTTP53CYP1A2 | |
| Biphenyl SCHEMBL16613189 | 0.92 | KMT2A (0.64) | KMT2AMEN1MAPTTP53CYP1A2 | |
| SCHEMBL3202302 | 0.91 | KMT2A (0.82) | KMT2AMEN1MAPTTP53CYP1A2 | |
| Hydrochloric Acid SCHEMBL25240263 | 0.89 | KMT2A (0.78) | KMT2AMEN1MAPTTP53CYP1A2 | |
| Bromide SCHEMBL8748216 | 0.89 | KMT2A (0.78) | KMT2AMEN1MAPTTP53CYP1A2 | |
| SCHEMBL30340106 | 0.88 | KMT2A (0.55) | KMT2AMEN1MAPTTP53CYP1A2 | |
| SCHEMBL8080641 | 0.86 | TP53 (0.56) | KMT2AMEN1MAPTTP53CYP1A2 | |
| Iodide SCHEMBL8080283 | 0.84 | KDM4E (0.57) | KMT2AMEN1MAPTTP53CYP1A2 | |
| Bromide SCHEMBL21750926 | 0.84 | KMT2A (0.54) | KMT2AMEN1MAPTTP53CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116103711-A | Forward and reverse pulse electrolytic nickel-phosphorus alloy solution, preparation method, electroplating method and nickel-phosphorus alloy coating | 安徽智备工业科技有限公司 | 2023-05-12 | — | — | CN | disclosed |
| US-20200062783-A1 | PHOTO LEWIS ACID GENERATOR | NIPPON SHOKUBAI CO., LTD. (JP) | 2020-02-27 | — | — | US | disclosed |
| CN-106661735-B | Palladium plating solution and palladium coating film obtained using the same | 日本高纯度化学株式会社 | 2019-12-10 | — | — | CN | disclosed |
| EP-1957093-B1 | NEUROPROTECTIVE AND NEURORESTORATIVE METHODS AND COMPOSITIONS | SHASHOUA VICTOR E (US) | 2017-04-12 | — | — | EP | disclosed |
| US-9295707-B2 | Neuroprotective and neurorestorative methods and compositions | SHASHOUA ANGELA (US) | 2016-03-29 | — | — | US | disclosed |
| US-20140018300-A1 | NEUROPROTECTIVE AND NEURORESTORATIVE METHODS AND COMPOSITIONS | ANGELA SHASHOUA (US) | 2014-01-16 | — | — | US | disclosed |
| US-8507439-B2 | Neuroprotective and neurorestorative method and compositions | SHASHOUA ANGELA (US) | 2013-08-13 | — | — | US | disclosed |
| WO-2012028578-A1 | SUBSTITUTED FUSED PYRIMIDINONES AND DIHYDROPYRIMIDINONES | BAYER CROPSCIENCE AG (DE) | 2012-03-08 | — | — | WO | disclosed |
| US-20120027781-A1 | Neuroprotective and neurorestorative method and compositions | SHASHOUA VICTOR E (US) | 2012-02-02 | — | — | US | disclosed |
| EP-1957093-A2 | NEUROPROTECTIVE AND NEURORESTORATIVE METHODS AND COMPOSITIONS | SHASHOUA, Victor E. (US) | 2008-08-20 | — | — | EP | disclosed |
| WO-2007027559-A2 | NEUROPROTECTIVE AND NEURORESTORATIVE METHODS AND COMPOSITIONS | SHASHOUA VICTOR E (US) | 2007-03-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140018300-A1 | NEUROPROTECTIVE AND NEURORESTORATIVE METHODS AND COMPOSITIONS | BDNF, NLN, NEFM | KMT2A 3664/4885MEN1 2712/4885MAPT 103/4885 |
| US-20120027781-A1 | Neuroprotective and neurorestorative method and compositions | BDNF, NLN, NEFM | KMT2A 3895/4885MEN1 2251/4885MAPT 108/4885 |
| US-20200062783-A1 | PHOTO LEWIS ACID GENERATOR | LEO1, LRRK2, LSG1 | KMT2A 1862/4885MEN1 1975/4885MAPT 3404/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.