Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | ACACB | O00763 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | CCR2 | P41597 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | MMP7 | P09237 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30471103 | 1.00 | RAB9A (0.47) | RAB9AGAAALDH1A1MEN1USP2 | |
| SCHEMBL30470970 | 0.96 | RAB9A (0.47) | RAB9AGAAALDH1A1MEN1USP2 | |
| SCHEMBL30471123 | 0.90 | ESR1 (0.49) | RAB9AGAAALDH1A1MEN1USP2 | |
| SCHEMBL25250671 | 0.90 | ESR1 (0.49) | RAB9AGAAALDH1A1MEN1USP2 | |
| SCHEMBL25250672 | 0.90 | ESR1 (0.49) | RAB9AGAAALDH1A1MEN1USP2 | |
| SCHEMBL25209545 | 0.89 | RAB9A (0.49) | RAB9AGAAALDH1A1MEN1USP2 | |
| SCHEMBL25267628 | 0.89 | RAB9A (0.49) | RAB9AGAAALDH1A1MEN1USP2 | |
| SCHEMBL30471075 | 0.89 | RAB9A (0.49) | RAB9AGAAALDH1A1MEN1USP2 | |
| SCHEMBL25250143 | 0.86 | ESR1 (0.51) | RAB9AGAAALDH1A1MEN1USP2 | |
| SCHEMBL25250140 | 0.86 | ESR1 (0.51) | RAB9AGAAALDH1A1MEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023094828-A1 | ANTAGONISTS OF CAV 2.3 | LARIO THERAPEUTICS LIMITED (GB) | 2023-06-01 | — | — | WO | disclosed |