Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 3/20 | 0.34 |
| ▸ | TAF1 | P21675 | 1/20 | 0.34 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.34 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | TTK | P33981 | 1/20 | 0.34 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.34 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.34 |
| ▸ | PRKCI | P41743 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27199525 | 0.98 | BRD4 (0.33) | BRD4TAF1BRPF1CREBBPCECR2 | |
| SCHEMBL25670818 | 0.81 | ALDH1A1 (0.33) | AURKATTKAURKBINCENPKDM4E | |
| Hydrochloric Acid SCHEMBL27199567 | 0.80 | CCNT1 (0.32) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL27199382 | 0.80 | ALDH1A1 (0.33) | MAPTKDM4EALDH1A1GAA | |
| SCHEMBL25752565 | 0.79 | DHODH (0.34) | BRD4MAPTCYP2C9KDM4EALDH1A1 | |
| SCHEMBL23487979 | 0.77 | BRD4 (0.34) | BRD4TAF1BRPF1CREBBPCECR2 | |
| SCHEMBL25670290 | 0.77 | BRD4 (0.34) | BRD4TAF1BRPF1CREBBPCECR2 | |
| Hydrochloric Acid SCHEMBL27199587 | 0.75 | MEN1 (0.33) | — | |
| Hydrochloric Acid SCHEMBL27199321 | 0.75 | ALDH1A1 (0.36) | MAPTCYP2C9KDM4EALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL27199639 | 0.75 | ALDH1A1 (0.34) | BRD4KDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023109120-A1 | TYK2 INHIBITORS AND COMPOSITIONS AND METHODS THEREOF | LYNK PHARMACEUTICALS CO. LTD. (CN) | 2023-06-22 | — | — | WO | disclosed |
| WO-2023108536-A1 | TYK2 INHIBITORS AND COMPOSITIONS AND METHODS THEREOF | LYNK PHARMACEUTICALS CO. LTD. (CN) | 2023-06-22 | — | — | WO | disclosed |