SCHEMBL2567192

SCHEMBL2567192

NCCOCc1ccccn1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HRH1 P35367 2/20 0.57
PARP10 Q53GL7 1/20 0.45
SYK P43405 2/20 0.44
SMN1; SMN2 Q16637 3/20 0.44
KDM4E B2RXH2 2/20 0.44
ALDH1A1 P00352 1/20 0.44
NPC1 O15118 1/20 0.41
LMNA P02545 1/20 0.41
RAB9A P51151 1/20 0.41
ABCB1 P08183 1/20 0.41
HTR1A P08908 1/20 0.41
DRD2 P14416 1/20 0.41
MAPT P10636 1/20 0.41
LIN28A Q9H9Z2 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
TAAR1 Q96RJ0 1/20 0.41
GRIN2D O15399 1/20 0.41
GRIN3B O60391 1/20 0.41
GRIN1 Q05586 1/20 0.41
GRIN2A Q12879 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30894456 0.87 HRH1 (0.59) HRH1PARP10SYKSMN1; SMN2KDM4E
SCHEMBL22401523 0.87 HRH1 (0.59) HRH1PARP10SYKSMN1; SMN2KDM4E
SCHEMBL28304769 0.84 HRH1 (0.55) HRH1PARP10SYKSMN1; SMN2KDM4E
SCHEMBL493397 0.83 HRH1 (0.52) HRH1PARP10SYKSMN1; SMN2KDM4E
Hydrochloric Acid SCHEMBL27710379 0.81 SMN1; SMN2 (0.50) HRH1PARP10SYKSMN1; SMN2KDM4E
SCHEMBL8904860 0.81 SMN1; SMN2 (0.47) HRH1PARP10SYKSMN1; SMN2KDM4E
SCHEMBL10263927 0.81 KDM4E (0.45) HRH1PARP10SYKSMN1; SMN2KDM4E
SCHEMBL19306253 0.81 SMN1; SMN2 (0.45) HRH1PARP10SYKSMN1; SMN2KDM4E
SCHEMBL18232031 0.79 SYK (0.44) HRH1SYKSMN1; SMN2KDM4EALDH1A1
SCHEMBL8904551 0.78 SMN1; SMN2 (0.45) HRH1PARP10SYKSMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2382274-B1 AQUEOUS COATING COMPOSITION COMPRISING PYRIDINE GROUP-CONTAINING ELECTROCOAT RESIN BASF COATINGS GMBH (DE) 2015-04-22 EP disclosed
EP-2382274-A1 PYRIDINE GROUP-CONTAINING ELECTROCOAT RESIN BASF Coatings GmbH (DE) 2011-11-02 EP disclosed
WO-2010077404-A1 PYRIDINE GROUP-CONTAINING ELECTROCOAT RESIN BASF COATINGS GMBH (US) 2010-07-08 WO disclosed
US-20100167069-A1 PYRIDINE GROUP-CONTAINING ELECTROCOAT RESIN BASF CORPORATION (US) 2010-07-01 US disclosed
US-20100167071-A1 PYRIDINE GROUP-CONTAINING ELECTROCOAT COMPOSITION WITH METAL OXIDE BASF CORPORATION (US) 2010-07-01 US disclosed