SCHEMBL25672008

SCHEMBL25672008

N#Cc1cccc(-c2ccc(-n3c4ccccc4c4cc(-c5ccc6c(c5)c5ccccc5n6-c5cccc(-c6ccccc6)c5)ccc43)cc2)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.45
ATM Q13315 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
ALDH1A3 P47895 1/20 0.40
MAP4K4 O95819 1/20 0.39
PTPN5 P54829 1/20 0.39
ADORA2A P29274 1/20 0.39
XDH P47989 1/20 0.39
SLC22A12 Q96S37 1/20 0.39
GABRA1 P14867 1/20 0.39
GABRG2 P18507 1/20 0.39
GABRB3 P28472 1/20 0.39
GABRA5 P31644 1/20 0.39
GABRA3 P34903 1/20 0.39
HRH3 Q9Y5N1 1/20 0.38
MCHR1 Q99705 1/20 0.38
ALDH1A1 P00352 5/20 0.38
CYP1A2 P05177 5/20 0.38
CYP3A4 P08684 4/20 0.38
CLK4 Q9HAZ1 4/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18767649 1.00 KDM4E (0.45) KDM4EATML3MBTL1ALDH1A3MAP4K4
SCHEMBL21984504 1.00 KDM4E (0.45) KDM4EATML3MBTL1ALDH1A3MAP4K4
SCHEMBL18623542 0.99 KDM4E (0.42) KDM4EATML3MBTL1ALDH1A3MAP4K4
SCHEMBL15248456 0.97 KDM4E (0.47) KDM4EATML3MBTL1ALDH1A3MAP4K4
SCHEMBL18805004 0.97 KDM4E (0.44) KDM4EATML3MBTL1ALDH1A3MAP4K4
SCHEMBL15248184 0.97 KDM4E (0.47) KDM4EATML3MBTL1ALDH1A3MAP4K4
SCHEMBL18767550 0.97 KDM4E (0.44) KDM4EATML3MBTL1ALDH1A3MAP4K4
SCHEMBL17178532 0.96 KDM4E (0.46) KDM4EATML3MBTL1ALDH1A3MAP4K4
SCHEMBL20754157 0.96 KDM4E (0.46) KDM4EATML3MBTL1ALDH1A3MAP4K4
SCHEMBL21531897 0.96 KDM4E (0.46) KDM4EATML3MBTL1ALDH1A3MAP4K4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230200233-A1 COMPOSITION, ELECTRONIC COMPOMENT AND ELECTRONIC DEVICE CONTAINING THE COMPOSITION SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-06-22 US disclosed
US-20230200233-A1 COMPOSITION, ELECTRONIC COMPOMENT AND ELECTRONIC DEVICE CONTAINING THE COMPOSITION SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-06-22 US disclosed