SCHEMBL20754157

SCHEMBL20754157

N#Cc1cccc(-n2c3ccccc3c3cc(-c4ccc5c(c4)c4ccccc4n5-c4ccc(-c5ccccc5)cc4)ccc32)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.46
ATM Q13315 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
IRAK4 Q9NWZ3 1/20 0.40
NOTUM Q6P988 1/20 0.39
ALDH1A3 P47895 1/20 0.38
RPS6KB1 P23443 1/20 0.38
MAP4K4 O95819 1/20 0.37
PTPN5 P54829 1/20 0.37
ADORA2A P29274 1/20 0.37
TSPO P30536 1/20 0.37
HDAC4 P56524 1/20 0.37
DRD2 P14416 1/20 0.37
DRD3 P35462 1/20 0.37
HRH3 Q9Y5N1 1/20 0.37
XDH P47989 1/20 0.36
SLC22A12 Q96S37 1/20 0.36
GABRA1 P14867 1/20 0.36
GABRG2 P18507 1/20 0.36
GABRB3 P28472 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18805001 1.00 KDM4E (0.46) KDM4EATML3MBTL1IRAK4NOTUM
SCHEMBL21531897 1.00 KDM4E (0.46) KDM4EATML3MBTL1IRAK4NOTUM
SCHEMBL18792296 0.99 KDM4E (0.45) KDM4EATML3MBTL1IRAK4NOTUM
SCHEMBL18804974 0.97 KDM4E (0.49) KDM4EATML3MBTL1IRAK4NOTUM
SCHEMBL15250611 0.97 KDM4E (0.49) KDM4EATML3MBTL1IRAK4NOTUM
SCHEMBL18633431 0.97 KDM4E (0.45) KDM4EATML3MBTL1IRAK4NOTUM
SCHEMBL21984504 0.96 KDM4E (0.45) KDM4EATML3MBTL1IRAK4ALDH1A3
SCHEMBL18767649 0.96 KDM4E (0.45) KDM4EATML3MBTL1IRAK4ALDH1A3
SCHEMBL25672008 0.96 KDM4E (0.45) KDM4EATML3MBTL1IRAK4ALDH1A3
SCHEMBL18698198 0.96 ATM (0.44) KDM4EATML3MBTL1IRAK4NOTUM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12018022-B2 Heterocyclic compound, organic light emitting diode comprising same, composition for organic layer of organic light emitting diode, and method for manufacturing organic light emitting diode LT MATERIALS CO., LTD. (KR) 2024-06-25 US disclosed
US-12018022-B2 Heterocyclic compound, organic light emitting diode comprising same, composition for organic layer of organic light emitting diode, and method for manufacturing organic light emitting diode LT MATERIALS CO., LTD. (KR) 2024-06-25 US disclosed
US-20240023355-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2024-01-18 US disclosed
US-20240023355-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2024-01-18 US disclosed
US-11827623-B2 Heterocyclic compound, organic light emitting diode comprising same, composition for organic layer of organic light emitting diode, and method for manufacturing organic light emitting diode LT MATERIALS CO., LTD. (KR) 2023-11-28 US disclosed
US-11827623-B2 Heterocyclic compound, organic light emitting diode comprising same, composition for organic layer of organic light emitting diode, and method for manufacturing organic light emitting diode LT MATERIALS CO., LTD. (KR) 2023-11-28 US disclosed
US-20230357209-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME, COMPOSITION FOR ORGANIC LAYER OF ORGANIC LIGHT-EMITTING DEVICE, AND METHOD FOR MANUFACTURING ORGANIC LIGHT-EMITTING DEVICE LT MATERIALS CO., LTD. (KR) 2023-11-09 US disclosed
US-20230357209-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME, COMPOSITION FOR ORGANIC LAYER OF ORGANIC LIGHT-EMITTING DEVICE, AND METHOD FOR MANUFACTURING ORGANIC LIGHT-EMITTING DEVICE LT MATERIALS CO., LTD. (KR) 2023-11-09 US disclosed
US-11800730-B2 Organic light emitting device LG CHEM, LTD. (KR) 2023-10-24 US disclosed
US-11800730-B2 Organic light emitting device LG CHEM, LTD. (KR) 2023-10-24 US disclosed
US-20210094914-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT EMITTING DIODE COMPRISING SAME, MANUFACTURING METHOD THEREFOR, AND COMPOSITION FOR ORGANIC LAYER LT MATERIALS CO., LTD. (KR) 2021-04-01 US disclosed
US-20210009894-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2021-01-14 US disclosed
US-10818848-B2 Organic light emitting device LG CHEM, LTD. (KR) 2020-10-27 US disclosed
US-20200266355-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME HEESUNG MATERIAL LTD. (KR) 2020-08-20 US disclosed
US-20200259098-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2020-08-13 US disclosed
WO-2020122576-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME, METHOD FOR MANUFACTURING SAME, AND COMPOSITION FOR ORGANIC MATERIAL LAYER 엘티소재주식회사 2020-06-18 WO disclosed
US-20200119285-A1 ORGANIC LIGHT EMITTING ELEMENT AND COMPOSITION FOR ORGANIC MATERIAL LAYER IN ORGANIC LIGHT EMITTING ELEMENT HEESUNG MATERIAL LTD. (KR) 2020-04-16 US disclosed
EP-3611173-A1 ORGANIC LIGHT EMITTING ELEMENT AND COMPOSITION FOR ORGANIC MATERIAL LAYER IN ORGANIC LIGHT EMITTING ELEMENT Heesung Material Ltd. (KR) 2020-02-19 EP disclosed
EP-3561891-A1 ORGANIC LIGHT EMITTING ELEMENT AND COMPOSITION FOR ORGANIC MATERIAL LAYER OF ORGANIC LIGHT EMITTING ELEMENT Heesung Material Ltd. (KR) 2019-10-30 EP disclosed
US-20190058131-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2019-02-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12018022-B2 Heterocyclic compound, organic light emitting diode comprising same, composition for organic layer of organic light emitting diode, and method for manufacturing organic light emitting diode ODC1, AOX1, CYP1B1 KDM4E 3003/4885ATM 3440/4885L3MBTL1 1524/4885
US-20240023355-A1 ORGANIC LIGHT EMITTING DEVICE CRY1, CRY2, CYP1A1 KDM4E 2823/4885ATM 3074/4885L3MBTL1 609/4885
US-20200119285-A1 ORGANIC LIGHT EMITTING ELEMENT AND COMPOSITION FOR ORGANIC MATERIAL LAYER IN ORGANIC LIGHT EMITTING ELEMENT CRY1, CYBA, L1CAM KDM4E 3489/4885ATM 2594/4885L3MBTL1 838/4885
US-20230357209-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME, COMPOSITION FOR ORGANIC LAYER OF ORGANIC LIGHT-EMITTING DEVICE, AND METHOD FOR MANUFACTURING ORGANIC LIGHT-EMITTING DEVICE CYP1A1, CYP1B1, ODC1 KDM4E 3424/4885ATM 3470/4885L3MBTL1 2006/4885
US-20200266355-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME CRY1, CRY2, CYP1A1 KDM4E 2341/4885ATM 2995/4885L3MBTL1 1142/4885
US-11800730-B2 Organic light emitting device CRY1, CRY2, MAP1LC3C KDM4E 1575/4885ATM 3898/4885L3MBTL1 84/4885
US-11827623-B2 Heterocyclic compound, organic light emitting diode comprising same, composition for organic layer of organic light emitting diode, and method for manufacturing organic light emitting diode ODC1, CYP1B1, CYP1A1 KDM4E 2724/4885ATM 3479/4885L3MBTL1 1453/4885
US-20210094914-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT EMITTING DIODE COMPRISING SAME, MANUFACTURING METHOD THEREFOR, AND COMPOSITION FOR ORGANIC LAYER CYP1B1, NOTUM, FAR1 KDM4E 2803/4885ATM 4112/4885L3MBTL1 1604/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.