SCHEMBL25673554

SCHEMBL25673554

COC(=O)C1(CC=N)CCC1

nearest known ligand 0.46

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 1/20 0.46
CYP4A11 Q02928 1/20 0.46
NPSR1 Q6W5P4 1/20 0.37
P2RX7 Q99572 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17725098 0.82 CYP4F2 (0.47) CYP4F2CYP4A11NPSR1P2RX7LMNA
SCHEMBL9687573 0.79 CYP4F2 (0.45) CYP4F2CYP4A11NPSR1
SCHEMBL8393649 0.78 CYP4F2 (0.50) CYP4F2CYP4A11NPSR1P2RX7LMNA
SCHEMBL2633876 0.77 CYP4F2 (0.50) CYP4F2CYP4A11NPSR1P2RX7LMNA
SCHEMBL25188768 0.77 CYP4F2 (0.50) CYP4F2CYP4A11NPSR1P2RX7LMNA
SCHEMBL9687113 0.77 CYP4F2 (0.42) CYP4F2CYP4A11NPSR1P2RX7
SCHEMBL9687116 0.77 CYP4F2 (0.42) CYP4F2CYP4A11NPSR1P2RX7
SCHEMBL2633828 0.76 CYP4F2 (0.49) CYP4F2CYP4A11NPSR1P2RX7LMNA
SCHEMBL34476313 0.76 CYP4F2 (0.49) CYP4F2CYP4A11NPSR1P2RX7LMNA
SCHEMBL3952155 0.75 CYP4F2 (0.56) CYP4F2CYP4A11NPSR1P2RX7LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023109540-A1 HETEROCYCLIC COMPOUND WITH AKT KINASE INHIBITORY ACTIVITY, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF 中国医药研究开发中心有限公司 2023-06-22 WO disclosed