Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9687116 | 1.00 | CYP4F2 (0.42) | CYP4F2CYP4A11NPSR1P2RX7ALDH1A1 | |
| SCHEMBL9687573 | 0.86 | CYP4F2 (0.45) | CYP4F2CYP4A11NPSR1 | |
| SCHEMBL9687019 | 0.80 | CYP2C19 (0.39) | ALDH1A1 | |
| SCHEMBL9687024 | 0.80 | CYP2C19 (0.39) | ALDH1A1 | |
| SCHEMBL17725098 | 0.78 | CYP4F2 (0.47) | CYP4F2CYP4A11NPSR1P2RX7 | |
| SCHEMBL6627940 | 0.77 | CYP4F2 (0.47) | CYP4F2CYP4A11NPSR1P2RX7 | |
| SCHEMBL25673554 | 0.77 | CYP4F2 (0.46) | CYP4F2CYP4A11NPSR1P2RX7 | |
| SCHEMBL9688054 | 0.75 | — | — | |
| SCHEMBL9688051 | 0.75 | — | — | |
| SCHEMBL25188768 | 0.73 | CYP4F2 (0.50) | CYP4F2CYP4A11NPSR1P2RX7ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5124343-A | Carbacyclins, process for the preparation thereof, and use thereof as medicinal agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1992-06-23 | — | — | US | disclosed |