Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 17/20 | 0.57 |
| ▸ | CTSL | P07711 | 2/20 | 0.51 |
| ▸ | CTSB | P07858 | 2/20 | 0.51 |
| ▸ | CTSK | P43235 | 2/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22585725 | 0.89 | USP30 (0.57) | USP30CTSLCTSBCTSK | |
| SCHEMBL25675753 | 0.88 | USP30 (0.56) | USP30CTSLCTSBCTSK | |
| SCHEMBL31017667 | 0.86 | USP30 (0.54) | USP30CTSLCTSBCTSKHDAC1 | |
| SCHEMBL25676690 | 0.86 | USP30 (0.54) | USP30CTSLCTSBCTSKHDAC1 | |
| SCHEMBL25676535 | 0.84 | USP30 (0.52) | USP30CTSLCTSBCTSK | |
| SCHEMBL22585874 | 0.83 | USP30 (0.53) | USP30CTSBCTSK | |
| SCHEMBL6485512 | 0.80 | CHRNA7 (0.52) | USP30HDAC1HDAC6 | |
| SCHEMBL6485506 | 0.80 | CHRNA7 (0.52) | USP30HDAC1HDAC6 | |
| SCHEMBL25676956 | 0.80 | USP30 (0.49) | USP30 | |
| SCHEMBL25675527 | 0.79 | USP30 (0.58) | USP30HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023099561-A1 | SUBSTITUTED N-CYANOPYRROLIDINES WITH ACTIVITY AS USP30 INHIBITORS | MISSION THERAPEUTICS LIMITED (GB) | 2023-06-08 | — | — | WO | disclosed |