Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 11/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 2/20 | 0.45 |
| ▸ | CNR2 | P34972 | 2/20 | 0.45 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.45 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.44 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27418109 | 0.88 | USP30 (0.56) | USP30HDAC6HDAC1HDAC4PARP1 | |
| SCHEMBL25675535 | 0.79 | USP30 (0.57) | USP30HDAC6HDAC1 | |
| SCHEMBL6485512 | 0.77 | CHRNA7 (0.52) | USP30HDAC6HDAC1CNR2 | |
| SCHEMBL29268982 | 0.76 | HDAC1 (0.42) | USP30HDAC6HDAC1 | |
| SCHEMBL29268985 | 0.76 | HDAC1 (0.42) | USP30HDAC6HDAC1 | |
| SCHEMBL30474034 | 0.76 | HDAC1 (0.42) | USP30HDAC6HDAC1 | |
| SCHEMBL18988111 | 0.75 | USP30 (0.64) | USP30HDAC6HDAC1 | |
| SCHEMBL30370293 | 0.75 | HDAC1 (0.54) | USP30HDAC6HDAC1RIPK1 | |
| SCHEMBL30230685 | 0.75 | MAP3K7 (0.42) | USP30HDAC6HDAC1 | |
| SCHEMBL7128786 | 0.74 | HDAC1 (0.51) | HDAC6HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023099561-A1 | SUBSTITUTED N-CYANOPYRROLIDINES WITH ACTIVITY AS USP30 INHIBITORS | MISSION THERAPEUTICS LIMITED (GB) | 2023-06-08 | — | — | WO | disclosed |