Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 13/20 | 0.60 |
| ▸ | PIK3CB | P42338 | 4/20 | 0.60 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.60 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.60 |
| ▸ | CSNK2A2 | P19784 | 4/20 | 0.42 |
| ▸ | CSNK2B | P67870 | 4/20 | 0.42 |
| ▸ | CSNK2A1 | P68400 | 4/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | PRKDC | P78527 | 1/20 | 0.42 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25220514 | 0.89 | PIK3CA (0.59) | PIK3CAPIK3CBPIK3CDPIK3CGMTOR | |
| SCHEMBL25683186 | 0.88 | PIK3CA (0.54) | PIK3CAPIK3CBPIK3CDPIK3CGMTOR | |
| SCHEMBL29202688 | 0.79 | PIK3CA (0.62) | PIK3CAPIK3CBMTORPRKDCPIK3C3 | |
| SCHEMBL30322285 | 0.79 | PIK3CA (0.62) | PIK3CAPIK3CBMTORPRKDCPIK3C3 | |
| SCHEMBL29202712 | 0.78 | PIK3CA (0.51) | PIK3CAPIK3CBPIK3CDPIK3CGMTOR | |
| SCHEMBL910282 | 0.78 | PIK3CA (0.75) | PIK3CAPIK3CBPIK3CDPIK3CGMTOR | |
| SCHEMBL30322406 | 0.76 | PIK3CA (0.57) | PIK3CAPIK3CBPIK3CDPIK3CGMTOR | |
| SCHEMBL25677257 | 0.76 | PIK3CA (0.54) | PIK3CAPIK3CBPIK3CDPIK3CGMTOR | |
| SCHEMBL30434657 | 0.76 | PIK3CA (0.74) | PIK3CAPIK3CBPIK3CDPIK3CGMTOR | |
| SCHEMBL25219256 | 0.76 | PIK3CA (0.74) | PIK3CAPIK3CBPIK3CDPIK3CGMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023104111-A1 | FUSED HETEROCYCLIC COMPOUNDS AS PI3KALPHA INHIBITORS | NANJING ZENSHINE PHARMACEUTICALS CO., LTD. (CN) | 2023-06-15 | — | — | WO | disclosed |