Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM2 | P50570 | 7/20 | 0.64 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.62 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.40 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3187610 | 0.77 | HRH3 (0.43) | DNM2NUDT1HRH3HRH4 | |
| SCHEMBL3187602 | 0.77 | HRH3 (0.43) | DNM2NUDT1HRH3HRH4 | |
| SCHEMBL14233966 | 0.74 | NUDT1 (0.71) | DNM2NUDT1HRH4MEN1KMT2A | |
| SCHEMBL12605112 | 0.73 | HRH3 (0.54) | DNM2NUDT1HRH3HRH4 | |
| SCHEMBL3209288 | 0.73 | CYP2D6 (0.64) | DNM2HRH3HRH4KMT2ACYP2D6 | |
| SCHEMBL16711168 | 0.71 | NUDT1 (0.67) | NUDT1HRH4MEN1KMT2AABL1 | |
| SCHEMBL1318447 | 0.71 | NUDT1 (0.67) | NUDT1HRH4MEN1KMT2AABL1 | |
| SCHEMBL2168204 | 0.71 | HRH3 (0.54) | DNM2HRH3HRH4CYP2D6 | |
| SCHEMBL1316806 | 0.69 | NUDT1 (0.64) | NUDT1HRH4MEN1KMT2AABL1 | |
| SCHEMBL604655 | 0.68 | HRH3 (0.45) | DNM2HRH3HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2382013-A1 | SELECTIVE HISTAMINE H4 RECEPTOR ANTAGONISTS FOR THE TREATMENT OF VESTIBULAR DISORDERS. | INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) | 2011-11-02 | — | — | EP | disclosed |
| WO-2010072829-A1 | SELECTIVE HISTAMINE H4 RECEPTOR ANTAGONISTS FOR THE TREATMENT OF VESTIBULAR DISORDERS. | INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) | 2010-07-01 | — | — | WO | disclosed |