Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 3/20 | 0.48 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.45 |
| ▸ | RET | P07949 | 3/20 | 0.42 |
| ▸ | JAK2 | O60674 | 3/20 | 0.42 |
| ▸ | DYRK3 | O43781 | 2/20 | 0.42 |
| ▸ | CDK1 | P06493 | 2/20 | 0.42 |
| ▸ | ROS1 | P08922 | 2/20 | 0.42 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.42 |
| ▸ | CDK2 | P24941 | 2/20 | 0.42 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.42 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.42 |
| ▸ | CLK2 | P49760 | 2/20 | 0.42 |
| ▸ | IRAK1 | P51617 | 2/20 | 0.42 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.42 |
| ▸ | NTRK3 | Q16288 | 2/20 | 0.42 |
| ▸ | SLK | Q9H2G2 | 2/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.42 |
| ▸ | CDC7 | O00311 | 1/20 | 0.42 |
| ▸ | PLK4 | O00444 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25678281 | 0.83 | PIK3CD (0.36) | PIK3CD | |
| SCHEMBL23150435 | 0.83 | PIK3CD (0.43) | PIK3CDPIK3CGRETJAK2DYRK3 | |
| SCHEMBL29589300 | 0.79 | BTK (0.60) | PIK3CDPIK3CGRETJAK2DYRK3 | |
| SCHEMBL19731411 | 0.79 | BTK (0.60) | PIK3CDPIK3CGRETJAK2DYRK3 | |
| SCHEMBL25678064 | 0.79 | PIK3CG (0.48) | PIK3CDPIK3CGRETJAK2DYRK3 | |
| SCHEMBL20552990 | 0.78 | ESR2 (0.48) | PIK3CDPIK3CGMAP4K4SRCBLK | |
| SCHEMBL29867555 | 0.78 | ESR2 (0.48) | PIK3CDPIK3CGMAP4K4SRCBLK | |
| SCHEMBL25678247 | 0.76 | PIK3CD (0.43) | PIK3CDPIK3CGRETJAK2DYRK3 | |
| SCHEMBL29867706 | 0.76 | PIK3CD (0.39) | PIK3CDPIK3CGJAK2SRCBTK | |
| SCHEMBL3832902 | 0.73 | ALDH1A1 (0.47) | PIK3CDPIK3CGRETJAK2DYRK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11685749-B2 | C26-linked rapamycin analogs as mTOR inhibitors | Revolution Medicines, Inc. (US) | 2023-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11685749-B2 | C26-linked rapamycin analogs as mTOR inhibitors | MTOR, RICTOR, RPTOR | PIK3CD 142/4885PIK3CG 191/4885RET 1666/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.