Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 2/20 | 0.36 |
| ▸ | SSTR4 | P31391 | 6/20 | 0.35 |
| ▸ | SSTR1 | P30872 | 4/20 | 0.35 |
| ▸ | FNTA | P49354 | 7/20 | 0.35 |
| ▸ | FNTB | P49356 | 7/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25678334 | 0.84 | TRPC3 (0.33) | CHRM4SSTR4SSTR1CYP1A2CYP2D6 | |
| SCHEMBL22169263 | 0.75 | DPP8 (0.52) | CHRM4FNTAFNTBCYP1A2 | |
| SCHEMBL14877507 | 0.69 | CYP2D6 (0.35) | CYP1A2CHRM2HTR1AADRA2ACYP2D6 | |
| SCHEMBL17033308 | 0.67 | SLC6A2 (0.40) | CYP1A2CHRM2HTR1AADRA2ACYP2D6 | |
| SCHEMBL31569049 | 0.66 | TRPC3 (0.45) | CYP2C9TSHRDRD1HTR2AHTR2C | |
| SCHEMBL25839998 | 0.64 | CYP19A1 (0.33) | CYP1A2CHRM2HTR1AADRA2ACYP2D6 | |
| SCHEMBL17034265 | 0.64 | CYP19A1 (0.41) | CYP1A2CHRM2HTR1AADRA2ACYP2D6 | |
| SCHEMBL8279301 | 0.64 | CYP19A1 (0.34) | CYP1A2CHRM2HTR1AADRA2ACYP2D6 | |
| SCHEMBL19498188 | 0.63 | CYP2D6 (0.33) | CYP1A2CHRM2HTR1AADRA2ACYP2D6 | |
| SCHEMBL25678889 | 0.62 | DPP8 (0.49) | CHRM4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230192690-A1 | 5,7-DIHYDRO-PYRROLO-PYRIDINE DERIVATIVES | PFIZER (US) | 2023-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230192690-A1 | 5,7-DIHYDRO-PYRROLO-PYRIDINE DERIVATIVES | CHRM1, CHRM5, CHRM2 | CHRM4 4/4885SSTR4 2167/4885SSTR1 2300/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.