Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 19/20 | 0.52 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.46 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14959570 | 0.79 | NAMPT (0.55) | NAMPTDPP8DPP9 | |
| SCHEMBL22169263 | 0.77 | DPP8 (0.52) | NAMPTDPP8DPP9 | |
| SCHEMBL25678403 | 0.77 | DPP8 (0.46) | NAMPTDPP8DPP9 | |
| SCHEMBL12162573 | 0.76 | NAMPT (0.56) | NAMPTDPP8DPP9 | |
| SCHEMBL3438648 | 0.74 | NOTUM (0.61) | NAMPTDPP8DPP9 | |
| SCHEMBL11929924 | 0.74 | DPP8 (0.53) | NAMPTDPP8DPP9 | |
| SCHEMBL29992618 | 0.73 | DPP8 (0.55) | NAMPTDPP8DPP9 | |
| SCHEMBL8203594 | 0.73 | DPP8 (0.55) | NAMPTDPP8DPP9 | |
| SCHEMBL17572894 | 0.71 | DPP8 (0.53) | NAMPTDPP8DPP9 | |
| SCHEMBL22169249 | 0.71 | DPP8 (0.53) | NAMPTDPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230192690-A1 | 5,7-DIHYDRO-PYRROLO-PYRIDINE DERIVATIVES | PFIZER (US) | 2023-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230192690-A1 | 5,7-DIHYDRO-PYRROLO-PYRIDINE DERIVATIVES | CHRM1, CHRM5, CHRM2 | NAMPT 1268/4885DPP8 3990/4885DPP9 4375/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.