Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 12/20 | 0.58 |
| ▸ | FGFR2 | P21802 | 3/20 | 0.57 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.56 |
| ▸ | KDR | P35968 | 2/20 | 0.56 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.55 |
| ▸ | KIT | P10721 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30446169 | 0.89 | AXL (0.70) | AXLFGFR2PDGFRAKDRPDGFRB | |
| SCHEMBL25680635 | 0.89 | AXL (0.55) | AXLFGFR2PDGFRAKDRPDGFRB | |
| SCHEMBL1592099 | 0.89 | AXL (0.70) | AXLFGFR2PDGFRAKDRPDGFRB | |
| SCHEMBL20770926 | 0.85 | FGFR2 (0.63) | AXLFGFR2PDGFRAKDRPDGFRB | |
| SCHEMBL22104162 | 0.83 | FGFR2 (0.68) | AXLFGFR2PDGFRAKDRPDGFRB | |
| SCHEMBL25681833 | 0.82 | EGFR (0.58) | FGFR2PDGFRAKDRKIT | |
| SCHEMBL20782657 | 0.82 | FGFR2 (0.60) | AXLFGFR2PDGFRAKDRPDGFRB | |
| SCHEMBL20782716 | 0.82 | AXL (0.57) | AXLFGFR2PDGFRAKDRPDGFRB | |
| SCHEMBL30446326 | 0.82 | FGFR2 (0.60) | AXLFGFR2PDGFRAKDRPDGFRB | |
| SCHEMBL25681912 | 0.81 | AXL (0.61) | AXLFGFR2PDGFRAKDRPDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230183239-A1 | ECTONUCLEOTIDE PYROPHOSPHATASE-PHOSPHODIESTERASE 1 (ENPP-1) INHIBITORS AND USES THEREOF | ABBVIE INC (US) | 2023-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230183239-A1 | ECTONUCLEOTIDE PYROPHOSPHATASE-PHOSPHODIESTERASE 1 (ENPP-1) INHIBITORS AND USES THEREOF | ENPP1, ENPP3, STING1 | AXL 3774/4885FGFR2 4496/4885PDGFRA 624/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.