⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27762403 | 0.78 | — | — | |
| SCHEMBL22531882 | 0.77 | — | — | |
| SCHEMBL4772491 | 0.76 | — | — | |
| SCHEMBL3942924 | 0.76 | — | — | |
| SCHEMBL28055068 | 0.74 | — | — | |
| SCHEMBL28131808 | 0.74 | — | — | |
| SCHEMBL363919 | 0.72 | — | — | |
| SCHEMBL22208402 | 0.72 | — | — | |
| SCHEMBL26657543 | 0.72 | DNM1 (0.30) | — | |
| SCHEMBL6379980 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3645007-A1 | METHODS OF TREATING CANCER WITH SMALL MOLECULE NF-KB INHIBITORS | Immunetarget, Inc. (US) | 2020-05-06 | — | — | EP | disclosed |
| CN-107266334-B | Fluorene compound, photopolymerization initiator containing the fluorene compound, and photosensitive composition containing the photopolymerization initiator | 大东凯米克斯株式会社 | 2020-04-24 | — | — | CN | disclosed |
| EP-3615533-A1 | FUSED INDAZOLE PYRIDONE COMPOUNDS AS ANTIVIRALS | Novartis AG (CH) | 2020-03-04 | — | — | EP | disclosed |
| WO-2019006002-A1 | METHODS OF TREATING CANCER WITH SMALL MOLECULE NF-KB INHIBITORS | IMMUNE TARGET, INC. (US) | 2019-01-03 | — | — | WO | disclosed |
| WO-2018198079-A1 | FUSED INDAZOLE PYRIDONE COMPOUNDS AS ANTIVIRALS | NOVARTIS AG (CH) | 2018-11-01 | — | — | WO | disclosed |
| CN-104684888-A | Fluorene compound, photopolymerization initiator containing the fluorene compound, and photosensitive composition containing the photopolymerization initiator | DAITO CHEMIX CORP | 2015-06-03 | — | — | CN | disclosed |
| EP-2382218-A1 | DELTA-5-DESATURASE INHIBITORS | Takeda Pharmaceutical Company Limited (JP) | 2011-11-02 | — | — | EP | disclosed |
| WO-2010087467-A1 | DELTA-5-DESATURASE INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-08-05 | — | — | WO | disclosed |
| EP-1919920-A2 | PENTACYCLIC KINASE INHIBITORS | Genentech, Inc. (US) | 2008-05-14 | — | — | EP | disclosed |
| WO-2007022102-A2 | PENTACYCLIC KINASE INHIBITORS | GENENTECH, INC. (US) | 2007-02-22 | — | — | WO | disclosed |