Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | WRN | Q14191 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.33 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.33 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25679992 | 0.94 | GSK3A (0.42) | GSK3AGSK3BALDH1A1HPGDCYP1A2 | |
| SCHEMBL25683883 | 0.94 | GSK3A (0.42) | GSK3AGSK3BALDH1A1HPGDCYP1A2 | |
| SCHEMBL30395097 | 0.77 | GSK3A (0.42) | GSK3AGSK3BALDH1A1HPGDCYP1A2 | |
| SCHEMBL25704255 | 0.77 | GSK3A (0.42) | GSK3AGSK3BALDH1A1HPGDCYP1A2 | |
| SCHEMBL27275549 | 0.77 | GSK3A (0.46) | GSK3AGSK3BALDH1A1HPGDCYP1A2 | |
| SCHEMBL25680048 | 0.76 | GSK3A (0.41) | GSK3AGSK3BALDH1A1HPGDCYP1A2 | |
| SCHEMBL18101913 | 0.76 | GSK3A (0.47) | GSK3AGSK3BALDH1A1HPGDCYP1A2 | |
| SCHEMBL30396141 | 0.75 | GSK3A (0.39) | GSK3AGSK3BALDH1A1HPGDCYP1A2 | |
| SCHEMBL20287639 | 0.74 | GSK3A (0.44) | GSK3AGSK3BALDH1A1HPGDCYP1A2 | |
| SCHEMBL22317387 | 0.72 | PTGS1 (0.42) | GSK3AGSK3BALDH1A1HPGDCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023109942-A1 | COMPOUND-LINKER CONSTRUCTS COMPRISING NOVEL COMPOUNDS USEFUL AS STING AGONISTS AND USES THEREOF | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2023-06-22 | — | — | WO | disclosed |