SCHEMBL25704255

SCHEMBL25704255

C[C@@H](O)CNC(=O)CN1C(=O)C=CC1=O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSK3A P49840 1/20 0.42
GSK3B P49841 1/20 0.42
KAT2A Q92830 1/20 0.38
KAT2B Q92831 1/20 0.38
ALDH1A1 P00352 3/20 0.36
BLM P54132 2/20 0.36
LMNA P02545 2/20 0.36
NPSR1 Q6W5P4 2/20 0.36
GMNN O75496 1/20 0.36
MAPT P10636 1/20 0.36
THPO P40225 1/20 0.36
PMP22 Q01453 1/20 0.36
MGLL Q99685 1/20 0.36
KMT2A Q03164 3/20 0.36
MEN1 O00255 2/20 0.36
HPGD P15428 3/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2C19 P33261 1/20 0.36
WRN Q14191 1/20 0.36
HIF1A Q16665 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30395097 1.00 GSK3A (0.42) GSK3AGSK3BKAT2AKAT2BALDH1A1
SCHEMBL25680048 0.85 GSK3A (0.41) GSK3AGSK3BKAT2AKAT2BALDH1A1
SCHEMBL25683883 0.82 GSK3A (0.42) GSK3AGSK3BKAT2AKAT2BALDH1A1
SCHEMBL25679992 0.82 GSK3A (0.42) GSK3AGSK3BKAT2AKAT2BALDH1A1
SCHEMBL3665093 0.78 GSK3A (0.52) GSK3AGSK3BALDH1A1BLMLMNA
SCHEMBL25680050 0.78 L3MBTL1 (0.49) LMNANPSR1KMT2AMEN1
SCHEMBL25680002 0.77 GSK3A (0.39) GSK3AGSK3BKAT2AKAT2BALDH1A1
SCHEMBL14664320 0.77 GSK3A (0.39) GSK3AGSK3BKAT2AKAT2BALDH1A1
SCHEMBL19795400 0.77 GSK3A (0.44) GSK3AGSK3BALDH1A1BLMLMNA
SCHEMBL15386866 0.77 KMT2A (0.56) GSK3AGSK3BALDH1A1BLMLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023109942-A1 COMPOUND-LINKER CONSTRUCTS COMPRISING NOVEL COMPOUNDS USEFUL AS STING AGONISTS AND USES THEREOF JACOBIO PHARMACEUTICALS CO., LTD. (CN) 2023-06-22 WO disclosed