Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CUL4A | Q13619 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9817941 | 0.80 | NPC1 (0.41) | ALDH1A1CYP1A2KDM4ENPC1MAPT | |
| SCHEMBL27694510 | 0.79 | ESR1 (0.41) | POLBALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL27714301 | 0.76 | BCL9 (0.41) | POLBALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL27365753 | 0.76 | CES2 (0.43) | POLBALDH1A1ALOX5KMT2AMEN1 | |
| SCHEMBL3159329 | 0.75 | CUL4A (0.41) | CUL4AALDH1A1ALOX5KDM4EMAPT | |
| SCHEMBL2483769 | 0.75 | CUL4A (0.47) | CUL4APOLBALDH1A1ALOX5KMT2A | |
| SCHEMBL2567583 | 0.74 | DAO (0.48) | POLBALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL20582495 | 0.73 | CES2 (0.41) | ALDH1A1ALOX5KMT2AKDM4EL3MBTL1 | |
| SCHEMBL2482717 | 0.72 | CUL4A (0.45) | CUL4APOLBALDH1A1KMT2AMEN1 | |
| SCHEMBL9817948 | 0.72 | CES2 (0.43) | POLBALDH1A1KMT2AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1899330-B9 | SUBSTITUTED GLYCINAMIDES HAVING AN ANTITHROMBOTIC AND FACTOR XA-INHIBITING EFFECT | BOEHRINGER INGELHEIM INT (DE) | 2011-11-09 | — | — | EP | disclosed |
| EP-1899330-B1 | SUBSTITUTED GLYCINAMIDES HAVING AN ANTITHROMBOTIC AND FACTOR XA-INHIBITING EFFECT | BOEHRINGER INGELHEIM INT (DE) | 2010-11-24 | — | — | EP | disclosed |