Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26445737 | 0.84 | MAPT (0.47) | HPGDTP53HDAC1HDAC2HDAC3 | |
| SCHEMBL25680280 | 0.83 | TP53 (0.46) | HPGDTP53HDAC1HDAC2HDAC3 | |
| SCHEMBL11420601 | 0.79 | MAPT (0.61) | HPGDTP53HDAC1HDAC2HDAC3 | |
| SCHEMBL25680273 | 0.79 | LTA4H (0.43) | TP53HDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL26445397 | 0.78 | MEN1 (0.42) | TP53MAPTALDH1A1L3MBTL1LMNA | |
| SCHEMBL17874890 | 0.77 | HPGD (0.47) | HPGDTP53HDAC1HDAC2HDAC3 | |
| SCHEMBL14962787 | 0.76 | CA12 (0.46) | HPGDMAPTALDH1A1NAMPTL3MBTL1 | |
| SCHEMBL21128695 | 0.74 | LTA4H (0.60) | HPGDMAPTALDH1A1LMNAMEN1 | |
| SCHEMBL13820074 | 0.74 | TP53 (0.43) | HPGDTP53MAPTALDH1A1NAMPT | |
| SCHEMBL24115701 | 0.74 | SMN1; SMN2 (0.41) | HPGDHDAC2MAPTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023109942-A1 | COMPOUND-LINKER CONSTRUCTS COMPRISING NOVEL COMPOUNDS USEFUL AS STING AGONISTS AND USES THEREOF | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2023-06-22 | — | — | WO | disclosed |