SCHEMBL25680409

SCHEMBL25680409

COCCOCC(=O)NCCCC[C@H](N)C(=O)N[C@H](C(=O)N[C@@H](C)C(C)=O)C(C)C

nearest known ligand 0.34

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ DPP7 Q9UHL4 2/20 0.34
▸ GLP1R P43220 8/20 0.34
▸ POLB P06746 1/20 0.34
▸ GNAI3 P08754 1/20 0.33
▸ GNAO1 P09471 1/20 0.33
▸ GNAI1 P63096 1/20 0.33
▸ MASP2 O00187 1/20 0.32
▸ F2 P00734 1/20 0.32
▸ MAPT P10636 1/20 0.31
▸ HSD17B10 Q99714 1/20 0.31
▸ FURIN P09958 2/20 0.31
▸ TSHR P16473 1/20 0.31
▸ LMNA P02545 1/20 0.30
▸ MAPK1 P28482 1/20 0.30
▸ PRSS1 P07477 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30408069 0.82 MAPT (0.36) DPP7GLP1RGNAI3GNAO1GNAI1
SCHEMBL27292946 0.82 TSHR (0.34) DPP7GLP1RGNAI3GNAO1GNAI1
SCHEMBL17833042 0.81 GLP1R (0.48) DPP7GLP1RGNAI3GNAO1GNAI1
SCHEMBL17833155 0.81 GLP1R (0.44) DPP7GLP1RGNAI3GNAO1GNAI1
SCHEMBL19707982 0.81 GLP1R (0.40) DPP7GLP1RGNAI3GNAO1GNAI1
SCHEMBL30407180 0.80 TDP1 (0.39) DPP7GLP1RPOLBGNAI3GNAO1
SCHEMBL30407749 0.78 TDP1 (0.38) DPP7GLP1RPOLBGNAI3GNAO1
SCHEMBL21568724 0.78 GLP1R (0.38) DPP7GLP1RGNAI3GNAO1GNAI1
SCHEMBL30407618 0.78 TDP1 (0.38) DPP7GLP1RPOLBGNAI3GNAO1
SCHEMBL30407214 0.77 MEN1 (0.35) GLP1RMASP2F2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023078021-A1 BCMA MONOCLONAL ANTIBODY AND THE ANTIBODY-DRUG CONJUGATE HANGZHOU DAC BIOTECH CO., LTD. (CN) 2023-05-11 — — WO disclosed
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