⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25683365 | 1.00 | — | — | |
| SCHEMBL5266553 | 0.72 | CA1 (0.32) | — | |
| SCHEMBL4813103 | 0.71 | TSHR (0.41) | — | |
| SCHEMBL25683478 | 0.69 | EPHX2 (0.33) | — | |
| SCHEMBL2057335 | 0.69 | — | — | |
| SCHEMBL24571680 | 0.69 | ALDH1A1 (0.39) | — | |
| SCHEMBL10391267 | 0.69 | — | — | |
| SCHEMBL10532234 | 0.69 | — | — | |
| SCHEMBL29443940 | 0.69 | — | — | |
| SCHEMBL14881593 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023114198-A2 | METHODS FOR THE SYNTHESIS OF COMPLEMENT FACTOR D INHIBITORS | ALEXION PHARMACEUTICALS, INC. (US) | 2023-06-22 | — | — | WO | disclosed |