Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15082725 | 0.96 | FAAH (0.45) | FAAHSMN1; SMN2TSHRALDH1A1MCL1 | |
| SCHEMBL30018622 | 0.96 | FAAH (0.45) | FAAHSMN1; SMN2TSHRALDH1A1MCL1 | |
| SCHEMBL24080462 | 0.92 | FAAH (0.42) | FAAHSMN1; SMN2TSHRALDH1A1MCL1 | |
| SCHEMBL16976898 | 0.85 | FAAH (0.59) | FAAHSMN1; SMN2TSHRGAAHPGD | |
| SCHEMBL25889978 | 0.84 | FAAH (0.47) | FAAHSMN1; SMN2TSHRMCL1HPGD | |
| SCHEMBL16560387 | 0.84 | FAAH (0.52) | FAAHTSHRMCL1GAAHPGD | |
| SCHEMBL2119757 | 0.83 | SMN1; SMN2 (0.46) | FAAHSMN1; SMN2TSHRALDH1A1MCL1 | |
| SCHEMBL15082321 | 0.83 | FAAH (0.50) | FAAHTSHRMCL1GAAHPGD | |
| SCHEMBL25582497 | 0.83 | FAAH (0.45) | FAAHTSHRALDH1A1MCL1GAA | |
| SCHEMBL27056720 | 0.83 | FAAH (0.50) | FAAHTSHRMCL1GAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023114198-A2 | METHODS FOR THE SYNTHESIS OF COMPLEMENT FACTOR D INHIBITORS | ALEXION PHARMACEUTICALS, INC. (US) | 2023-06-22 | — | — | WO | disclosed |