SCHEMBL25680916

SCHEMBL25680916

CC(=O)NC1CN(C)CC1NC(C)=O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
OGA O60502 4/20 0.41
SMN1; SMN2 Q16637 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37
PSEN1 P49768 3/20 0.36
PSEN2 P49810 3/20 0.36
APH1B Q8WW43 3/20 0.36
NCSTN Q92542 3/20 0.36
APH1A Q96BI3 3/20 0.36
PSENEN Q9NZ42 3/20 0.36
ATM Q13315 1/20 0.34
ALDH1A1 P00352 2/20 0.34
GRM6 O15303 2/20 0.33
GRM2 Q14416 2/20 0.33
GRM3 Q14832 2/20 0.33
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
CA12 O43570 1/20 0.33
CA9 Q16790 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25022569 0.87 SSTR4 (0.39) OGASMN1; SMN2NPSR1CYP2C9CYP2C19
SCHEMBL25022640 0.87 SSTR4 (0.39) OGASMN1; SMN2NPSR1CYP2C9CYP2C19
SCHEMBL8280849 0.87 OGA (0.41) OGASMN1; SMN2NPSR1CYP2C9CYP2C19
SCHEMBL24928079 0.85 OGA (0.36) OGASMN1; SMN2NPSR1CYP2C9CYP2C19
SCHEMBL10513014 0.85 OGA (0.36) OGASMN1; SMN2NPSR1CYP2C9CYP2C19
SCHEMBL10513011 0.85 OGA (0.36) OGASMN1; SMN2NPSR1CYP2C9CYP2C19
SCHEMBL15521326 0.83 OGA (0.45) OGASMN1; SMN2NPSR1CYP2C9CYP2C19
SCHEMBL15521173 0.83 OGA (0.45) OGASMN1; SMN2NPSR1CYP2C9CYP2C19
SCHEMBL15521171 0.83 OGA (0.45) OGASMN1; SMN2NPSR1CYP2C9CYP2C19
SCHEMBL26620645 0.83 OGA (0.36) OGASMN1; SMN2NPSR1CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3707145-B1 GLUCOSE-SENSITIVE ALBUMIN-BINDING DERIVATIVES NOVO NORDISK AS (DK) 2023-06-21 EP disclosed