Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGA | O60502 | 4/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.33 |
| ▸ | HEXA | P06865 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | NSD2 | O96028 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.30 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.30 |
| ▸ | GRM6 | O15303 | 1/20 | 0.30 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.30 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15521173 | 0.88 | OGA (0.45) | OGACYP2C9CYP2C19SMN1; SMN2NPSR1 | |
| SCHEMBL15521326 | 0.88 | OGA (0.45) | OGACYP2C9CYP2C19SMN1; SMN2NPSR1 | |
| SCHEMBL15521171 | 0.88 | OGA (0.45) | OGACYP2C9CYP2C19SMN1; SMN2NPSR1 | |
| SCHEMBL25680916 | 0.87 | OGA (0.41) | OGACYP2C9CYP2C19SMN1; SMN2NPSR1 | |
| SCHEMBL14426720 | 0.86 | OGA (0.44) | OGACYP2C9CYP2C19SMN1; SMN2NPSR1 | |
| SCHEMBL15980408 | 0.82 | OGA (0.38) | OGACYP2C9CYP2C19SMN1; SMN2NPSR1 | |
| SCHEMBL3260696 | 0.81 | OGA (0.35) | OGACYP2C9CYP2C19ALDH1A1NSD2 | |
| SCHEMBL3260694 | 0.81 | OGA (0.35) | OGACYP2C9CYP2C19ALDH1A1NSD2 | |
| SCHEMBL3260691 | 0.81 | OGA (0.35) | OGACYP2C9CYP2C19ALDH1A1NSD2 | |
| SCHEMBL3260689 | 0.81 | OGA (0.35) | OGACYP2C9CYP2C19ALDH1A1NSD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005080389-A1 | INDAZOLE-CARBOXAMIDE COMPOUNDS AS 5-HT4 RECEPTOR AGONISTS | THERAVANCE, INC. (US) | 2005-09-01 | — | — | WO | disclosed |