⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24473427 | 1.00 | — | — | |
| SCHEMBL13465635 | 0.79 | — | — | |
| SCHEMBL16312962 | 0.79 | — | — | |
| SCHEMBL19003910 | 0.76 | — | — | |
| SCHEMBL13351287 | 0.75 | — | — | |
| SCHEMBL6576623 | 0.74 | — | — | |
| SCHEMBL13350922 | 0.73 | — | — | |
| SCHEMBL11685724 | 0.73 | CTSK (0.38) | — | |
| SCHEMBL21236997 | 0.72 | — | — | |
| SCHEMBL19277381 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230203061-A1 | BRIDGED TRICYCLIC CARBAMOYLPYRIDONE COMPOUNDS AND THEIR PHARMACEUTICAL USE | GILEAD SCIENCES, INC. | 2023-06-29 | — | — | US | disclosed |