Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | PLAAT3 | P53816 | 2/20 | 0.49 |
| ▸ | PLAAT5 | Q96KN8 | 2/20 | 0.49 |
| ▸ | PLAAT2 | Q9NWW9 | 2/20 | 0.49 |
| ▸ | PLAAT4 | Q9UL19 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | F13A1 | P00488 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13930810 | 0.84 | KDM4E (0.47) | SMN1; SMN2HPGDKDM4EF13A1KMT2A | |
| SCHEMBL19088829 | 0.82 | ESRRG (0.50) | SMN1; SMN2HPGDKDM4EF13A1ALDH1A1 | |
| SCHEMBL6307134 | 0.82 | NPC1 (0.59) | NPC1RAB9ASMN1; SMN2PLAAT5PLAAT4 | |
| SCHEMBL23813137 | 0.81 | NPC1 (0.54) | NPC1RAB9ASMN1; SMN2PLAAT3PLAAT5 | |
| SCHEMBL661278 | 0.80 | KDM4E (0.72) | NPC1RAB9ASMN1; SMN2PLAAT3PLAAT5 | |
| Water SCHEMBL17767324 | 0.80 | NPC1 (0.57) | NPC1RAB9ASMN1; SMN2PLAAT5PLAAT4 | |
| SCHEMBL20911609 | 0.80 | NPC1 (0.53) | NPC1RAB9ASMN1; SMN2PLAAT3PLAAT5 | |
| SCHEMBL13369666 | 0.79 | SMN1; SMN2 (0.53) | NPC1RAB9ASMN1; SMN2HPGDKDM4E | |
| Hydrochloric Acid SCHEMBL1421841 | 0.78 | KDM4E (0.70) | NPC1RAB9ASMN1; SMN2PLAAT3PLAAT5 | |
| SCHEMBL16681873 | 0.78 | NPC1 (0.74) | NPC1RAB9ASMN1; SMN2PLAAT3PLAAT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3632443-B1 | ANTI-TUMOR EFFECT POTENTIATOR USING A BIPHENYL COMPOUND | TAIHO PHARMACEUTICAL CO LTD (JP) | 2023-06-07 | — | — | EP | disclosed |