⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6671727 | 1.00 | — | — | |
| SCHEMBL2568464 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL4771535 | 0.97 | DPP4 (0.50) | — | |
| Hydrochloric Acid SCHEMBL19900820 | 0.97 | DPP4 (0.50) | — | |
| Trifluoroacetic Acid SCHEMBL27230994 | 0.85 | SLC7A5 (0.43) | — | |
| Trifluoroacetic Acid SCHEMBL27210261 | 0.85 | SLC7A5 (0.43) | — | |
| SCHEMBL19503059 | 0.84 | DPP4 (0.53) | — | |
| SCHEMBL19522543 | 0.84 | DPP4 (0.53) | — | |
| SCHEMBL20990277 | 0.82 | DPP4 (0.52) | — | |
| Trifluoroacetic Acid SCHEMBL27923223 | 0.82 | DPP4 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 209 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11980669-B2 | Capped and uncapped antibody cysteines, and their use in antibody-drug conjugation | PFIZER, INC. (US) | 2024-05-14 | — | — | US | claimed |
| CN-115819260-B | Synthesis process of sitagliptin intermediate | 江苏阿尔法药业股份有限公司 | 2024-03-19 | — | — | CN | claimed |
| CN-116137818-A | Para-amino-benzyl linkers, methods of making and use thereof in conjugates | 法国施维雅药厂 | 2023-05-19 | — | — | CN | claimed |
| CN-114845738-A | Treatment with site-specific HER2 antibody-drug conjugates | 辉瑞大药厂 | 2022-08-02 | — | — | CN | claimed |
| CN-108473591-B | Site-specific HER2 antibody drug conjugates | 辉瑞公司 | 2022-01-28 | — | — | CN | claimed |
| WO-2012143499-A2 | NOVEL BINDER-DRUG CONJUGATES (ADCS) AND THEIR USE | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2012-10-26 | — | — | WO | claimed |
| WO-2011149995-A1 | NOVEL SUBSTITUTED OCTAHYDROCYCLOPENTA [C]PYRROL-4-AMINES AS CALCIUM CHANNEL BLOCKERS | ABBOTT LABORATORIES (US) | 2011-12-01 | — | — | WO | claimed |
| WO-2004026293-A2 | HEMIASTERLIN DERIVATIVES FOR TREATING RESISTANT TUMORS | WYETH HOLDINGS CORPORATION (US) | 2004-04-01 | — | — | WO | claimed |
| EP-0678503-B1 | Delta-amino-gamma-hydroxy-omega-aryl alkanoic acid amides with enzyme especially renin inhibiting activities | NOVARTIS AG (CH) | 1999-09-01 | — | — | EP | claimed |
| US-20250339550-A1 | ANTIBODY-DRUG CONJUGATES TARGETING HUMAN CLAUDIN 18.2 | LANOVA MEDICINES LTD COMPANY (CN) | 2025-11-06 | — | — | US | disclosed |
| EP-4619037-A1 | SMALL MOLECULE-DRUG-CONJUGATES CLEAVABLE IN A TUMOR MICROENVIRONMENT | Lerchen, Hans-Georg (DE) | 2025-09-24 | — | — | EP | disclosed |
| EP-4619044-A1 | ANTIBODY-DRUG-CONJUGATES CLEAVABLE IN A TUMOR MICROENVIRONMENT | Lerchen, Hans-Georg (DE) | 2025-09-24 | — | — | EP | disclosed |
| CN-120192413-A | Antibody targeting FR alpha or antibody coupling drug and application thereof | 三优生物医药(上海)有限公司 | 2025-06-24 | — | — | CN | disclosed |
| US-20250163164-A1 | ANTI-IL-13RA2 MONOCLONAL ANTIBODIES AND USES THEREOF | LANOVA MEDICINES DEVELOPMENT CO., LTD. (CN) | 2025-05-22 | — | — | US | disclosed |
| WO-1993009102-A1 | HETEROARYLPIPERIDINES, PYRROLIDINES AND PIPERAZINES AND THEIR USE AS ANTIPSYCHOTICS AND ANALGETICS | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1993-05-13 | — | — | WO | disclosed |
| US-5103009-A | Method for the preparation of herbicidal intermediates | AMERICAN CYANAMID COMPANY (US) | 1992-04-07 | — | — | US | disclosed |
| EP-0304134-A2 | Magnetic resin composition | DSM N.V. (NL) | 1989-02-22 | — | — | EP | disclosed |
| EP-0137351-B1 | Process for the enantioselective préparation of acyclic alpha-alkylated alpha-aminecarboxylic acids | Degussa Aktiengesellschaft (DE) | 1987-03-04 | — | — | EP | disclosed |
| US-4585892-A | Process for the enantioselective production of α-alkylated, acyclic α-aminocarboxylic acids | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1986-04-29 | — | — | US | disclosed |
| EP-0137351-A2 | Process for the enantioselective préparation of acyclic alpha-alkylated alpha-aminecarboxylic acids | Degussa Aktiengesellschaft (DE) | 1985-04-17 | — | — | EP | disclosed |