Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.58 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.58 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.50 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25669204 | 0.87 | SIGMAR1 (0.47) | SIGMAR1TMEM97OPRM1SSTR5CYP3A4 | |
| SCHEMBL24993856 | 0.82 | SIGMAR1 (0.54) | SIGMAR1OPRM1SSTR5CYP2D6TSHR | |
| SCHEMBL19693299 | 0.75 | CYP2D6 (0.54) | CYP3A4CYP2D6TSHR | |
| SCHEMBL10111366 | 0.74 | SSTR5 (0.61) | SIGMAR1TMEM97SSTR5 | |
| SCHEMBL5243003 | 0.74 | CYP2D6 (0.67) | SIGMAR1CYP3A4CYP2D6TSHR | |
| SCHEMBL25669421 | 0.73 | TMEM97 (0.50) | SIGMAR1TMEM97POLB | |
| SCHEMBL24994297 | 0.73 | CYP2D6 (0.55) | SIGMAR1OPRM1CYP3A4CYP2D6TSHR | |
| SCHEMBL1732446 | 0.73 | CYP2D6 (0.65) | SIGMAR1CYP3A4CYP2D6TSHR | |
| SCHEMBL9851544 | 0.72 | CYP2D6 (0.69) | CYP3A4CYP2D6TSHRLMNA | |
| SCHEMBL10111365 | 0.72 | SSTR5 (0.61) | SIGMAR1TMEM97OPRM1SSTR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023109883-A1 | AROMATIC HETEROCYCLE-SUBSTITUTED COMPOUNDS, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翊石医药科技有限公司 | 2023-06-22 | — | — | WO | disclosed |