Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 8/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | BTK | Q06187 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 2/20 | 0.44 |
| ▸ | CTSK | P43235 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30199256 | 0.87 | DRD2 (0.48) | DRD2EPHX1KDM1AMAOBBTK | |
| SCHEMBL28604444 | 0.85 | TDP1 (0.50) | DRD2EPHX1KDM1AMAOBBTK | |
| SCHEMBL14231252 | 0.85 | DRD2 (0.47) | DRD2EPHX1KDM1AMAOBBTK | |
| SCHEMBL19445904 | 0.85 | DRD2 (0.49) | DRD2EPHX1KDM1AMAOBBTK | |
| SCHEMBL21482088 | 0.85 | DRD2 (0.49) | DRD2EPHX1KDM1AMAOBBTK | |
| SCHEMBL22488855 | 0.85 | DRD2 (0.49) | DRD2EPHX1KDM1AMAOBBTK | |
| SCHEMBL4805690 | 0.84 | DRD2 (0.46) | DRD2EPHX1KDM1AMAOBBTK | |
| SCHEMBL4805695 | 0.84 | DRD2 (0.46) | DRD2EPHX1KDM1AMAOBBTK | |
| SCHEMBL22489272 | 0.84 | DRD2 (0.48) | DRD2EPHX1KDM1AMAOBBTK | |
| SCHEMBL23185506 | 0.83 | DRD2 (0.50) | DRD2EPHX1KDM1AMAOBBTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023110700-A1 | DIHYDROFUROPYRIDINE DERIVATIVES AS RHO-KINASE INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2023-06-22 | — | — | WO | disclosed |