SCHEMBL2568930

SCHEMBL2568930

COc1cc(C=NO)ccc1O

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.62
TRPA1 O75762 1/20 0.62
TRIM24 O15164 1/20 0.62
HPGD P15428 1/20 0.62
ALDH5A1 P51649 1/20 0.62
ABAT P80404 1/20 0.62
TDP1 Q9NUW8 1/20 0.62
TRIM33 Q9UPN9 1/20 0.62
TYR P14679 1/20 0.61
AMY1A P0DUB6 1/20 0.60
MEN1 O00255 2/20 0.59
KMT2A Q03164 2/20 0.59
MMP9 P14780 1/20 0.59
TTR P02766 1/20 0.59
MAPT P10636 3/20 0.57
NFKB1 P19838 2/20 0.57
NFKB2 Q00653 2/20 0.57
RELA Q04206 2/20 0.57
NPC1 O15118 1/20 0.57
LMNA P02545 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5075035 1.00 ALDH1A1 (0.62) ALDH1A1TRPA1TRIM24HPGDALDH5A1
SCHEMBL7990948 1.00 ALDH1A1 (0.62) ALDH1A1TRPA1TRIM24HPGDALDH5A1
Methoxymethane SCHEMBL28680903 0.98 ALDH1A1 (0.61) ALDH1A1TRPA1TRIM24HPGDALDH5A1
SCHEMBL591866 0.87 MAPT (0.73) ALDH1A1TRPA1TRIM24HPGDALDH5A1
SCHEMBL31021335 0.87 MAPT (0.73) ALDH1A1TRPA1TRIM24HPGDALDH5A1
SCHEMBL2565545 0.85 CYP1A2 (0.77) ALDH1A1KMT2AMAPTSMN1; SMN2MPO
SCHEMBL13269205 0.85 CYP1A2 (0.77) ALDH1A1KMT2AMAPTSMN1; SMN2MPO
SCHEMBL2565544 0.85 CYP1A2 (0.77) ALDH1A1KMT2AMAPTSMN1; SMN2MPO
SCHEMBL16864095 0.85 ALDH1A1 (0.62) ALDH1A1TRPA1TRIM24HPGDALDH5A1
SCHEMBL12045234 0.85 ALDH1A1 (0.62) ALDH1A1TRPA1TRIM24HPGDALDH5A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117757405-A Preparation method of high-performance PUR hot melt adhesive 广州市嘉雁粘合剂有限公司 2024-03-26 CN claimed
CN-113149927-B Vanillin isoxazole compound and preparation method and application thereof 北京农学院 2022-10-28 CN claimed
CN-113149927-A Vanillin isoxazole compound and preparation method and application thereof 北京农学院 2021-07-23 CN claimed
CN-106366004-A Preparation method for vanillylamine hydrochloride 河南省化工研究所有限责任公司 2017-02-01 CN claimed
US-6395260-B1 SKIN LIGHTENING COMPOSITIONS HAARMANN & REIMER GMBH (DE) 2002-05-28 US claimed
CN-1279939-A Local use cosmetic compositions containing benzaldoximes compounds HAARMANN & REIMER GMBH (DE) 2001-01-17 CN claimed
EP-1066821-A1 Topical cosmetic product containing benzaldoxims HAARMANN & REIMER GMBH (DE) 2001-01-10 EP claimed
EP-4587583-A1 COVALENTLY MODIFIED TEMPLATE-INDEPENDENT DNA POLYMERASE AND METHODS OF USE THEREOF The Charles Stark Draper Laboratory, Inc. (US) 2025-07-23 EP disclosed
US-20250034443-A1 HYDROXY/AMINO OXIME-BASED HOT MELT ADHESIVES FOR REWORK, REPAIR, AND RECYCLE CONAGEN INC. (US) 2025-01-30 US disclosed
US-20240229089-A1 A process for enzymatic synthesis of amides from amines and carboxylic acids or esters XP CHEMISTRIES AB (SE) 2024-07-11 US disclosed
CN-113636953-B Preparation method of O-/N-alkyl substituted hydroxylamine salt 诚弘制药(威海)有限责任公司 2024-04-19 CN disclosed
CN-117757405-A Preparation method of high-performance PUR hot melt adhesive 广州市嘉雁粘合剂有限公司 2024-03-26 CN disclosed
WO-2024059703-A1 COVALENTLY MODIFIED TEMPLATE-INDEPENDENT DNA POLYMERASE AND METHODS OF USE THEREOF THE CHARLES STARK DRAPER LABORATORY, INC. (US) 2024-03-21 WO disclosed
EP-1008593-A1 Benzylidene-gamma-butyrolactones, process for their production and use thereof as UV absorbers HAARMANN & REIMER GMBH (DE) 2000-06-14 EP disclosed
US-5393921-A Process for synthesizing O-substituted oxime compounds and conversion to the corresponding O-substituted hydroxylamine THE GILLETTE COMPANY (US) 1995-02-28 US disclosed
WO-1995001952-A1 PROCESS FOR SYNTHESIZING O-SUBSTITUTED OXIME COMPOUNDS AND CONVERSION TO THE CORRESPONDING O-SUBSTITUTED HYDROXYLAMINE THE GILLETTE COMPANY (US) 1995-01-19 WO disclosed
EP-0417167-A1 PROCESS FOR THE SYNTHESIS OF O-SUBSTITUTED OXIME COMPOUNDS AlliedSignal Inc. (US) 1991-03-20 EP disclosed
WO-1989011473-A1 PROCESS FOR THE SYNTHESIS OF O-SUBSTITUTED OXIME COMPOUNDS ALLIED-SIGNAL INC. (US) 1989-11-30 WO disclosed
EP-0158159-B1 PROCESS FOR THE SYNTHESIS OF O-SUBSTITUTED OXIME COMPOUNDS AND THE CONVERSION THEREOF INTO THE CORRESPONDING HYDROXYLAMINE O-SUBSTITUTED AlliedSignal Inc. (US) 1988-10-05 EP disclosed
EP-0158159-A1 Process for the synthesis of o-substituted oxime compounds and the conversion thereof into the corresponding hydroxylamine o-substituted AlliedSignal Inc. (US) 1985-10-16 EP disclosed