Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | P4HTM | Q9NXG6 | 8/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | USP7 | Q93009 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.40 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | PI4KA | P42356 | 1/20 | 0.40 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27122601 | 0.81 | SMYD3 (0.52) | MAOBP4HTM | |
| SCHEMBL30871624 | 0.79 | HDAC3 (0.41) | P4HTMNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL22854273 | 0.79 | NPC1 (0.45) | P4HTMNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL428478 | 0.75 | NPC1 (0.49) | P4HTMNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL2642502 | 0.74 | PARP1 (0.50) | MAOBP4HTMNPC1RAB9AALDH1A1 | |
| SCHEMBL22227949 | 0.74 | P4HTM (0.55) | P4HTMNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL17315227 | 0.74 | PTK2 (0.53) | NPC1RAB9ASMN1; SMN2ALDH1A1GAA | |
| SCHEMBL25693772 | 0.74 | BRD4 (0.38) | MAOBSMN1; SMN2ALDH1A1GAASYK | |
| SCHEMBL4314837 | 0.73 | NPC1 (0.41) | P4HTMNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL17091245 | 0.73 | PARP1 (0.49) | MAOBP4HTMNPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024050370-A1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE THEREOF | 1CBIO, INC. (US) | 2024-03-07 | — | — | WO | disclosed |
| WO-2023122140-A1 | PARP1 INHIBITORS | SYNNOVATION THERAPEUTICS, INC. (US) | 2023-06-29 | — | — | WO | disclosed |