Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF18A | Q8NI77 | 20/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25692752 | 0.94 | KIF18A (0.74) | KIF18A | |
| SCHEMBL25690818 | 0.90 | KIF18A (0.72) | KIF18A | |
| SCHEMBL25693412 | 0.88 | KIF18A (0.81) | KIF18A | |
| SCHEMBL22152128 | 0.87 | KIF18A (0.74) | KIF18A | |
| SCHEMBL22148699 | 0.87 | KIF18A (0.74) | KIF18A | |
| SCHEMBL22152152 | 0.86 | KIF18A (0.76) | KIF18A | |
| SCHEMBL25695897 | 0.86 | KIF18A (0.74) | KIF18A | |
| SCHEMBL25690810 | 0.86 | KIF18A (0.74) | KIF18A | |
| SCHEMBL24319640 | 0.85 | KIF18A (1.00) | KIF18A | |
| SCHEMBL29608855 | 0.85 | KIF18A (1.00) | KIF18A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3897855-B1 | KIF18A INHIBITORS | AMGEN INC (US) | 2023-06-07 | — | — | EP | disclosed |