Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDUA | P35475 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18819594 | 0.94 | IDUA (0.34) | IDUAMAPK1 | |
| SCHEMBL13134061 | 0.81 | IDUA (0.38) | IDUAMAPK1 | |
| SCHEMBL13134062 | 0.81 | IDUA (0.38) | IDUAMAPK1 | |
| SCHEMBL17256226 | 0.81 | IDUA (0.38) | IDUAMAPK1 | |
| SCHEMBL9385852 | 0.77 | IDUA (0.38) | IDUA | |
| SCHEMBL23358401 | 0.75 | PYGB (0.44) | — | |
| SCHEMBL25696296 | 0.75 | IDUA (0.34) | IDUA | |
| SCHEMBL21386691 | 0.75 | IDUA (0.34) | IDUA | |
| SCHEMBL18820165 | 0.75 | PYGB (0.44) | — | |
| SCHEMBL12764243 | 0.72 | PYGB (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122494-A1 | COMPOSITIONS AND METHODS OF USE TO TREAT 12-LIPOXYGENASE (12-LOX) MEDIATED DISEASES | VERALOX THERAPEUTICS (US) | 2023-06-29 | — | — | WO | disclosed |