Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 8/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.41 |
| ▸ | HPGDS | O60760 | 2/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CD38 | P28907 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.38 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.38 |
| ▸ | HTR3B | O95264 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.38 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30273150 | 0.84 | PARP1 (0.45) | HSD11B1HPGDSPARP1CHEK1SMYD3 | |
| SCHEMBL25235207 | 0.84 | PARP1 (0.45) | HSD11B1HPGDSPARP1CHEK1SMYD3 | |
| Hydrochloric Acid SCHEMBL31552839 | 0.83 | PARP1 (0.44) | HSD11B1HPGDSPARP1CHEK1SMYD3 | |
| SCHEMBL25323925 | 0.82 | PARP1 (0.52) | HSD11B1HPGDSPARP1CHEK1CD38 | |
| SCHEMBL31465719 | 0.82 | HSD11B1 (0.43) | HSD11B1HPGDSPARP1CHEK1SMYD3 | |
| Hydrochloric Acid SCHEMBL30720140 | 0.82 | CRBN (0.47) | — | |
| Hydrochloric Acid SCHEMBL25320690 | 0.81 | PARP1 (0.51) | HSD11B1HPGDSPARP1CHEK1SMYD3 | |
| Hydrochloric Acid SCHEMBL31552854 | 0.81 | SMYD3 (0.43) | HSD11B1HPGDSPARP1CHEK1SMYD3 | |
| SCHEMBL31465737 | 0.76 | PARP1 (0.45) | PARP1CD38CYP2D6CYP2B6CYP2C19 | |
| SCHEMBL29085174 | 0.73 | SCN9A (0.43) | CNR2HPGDSPARP1HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122140-A1 | PARP1 INHIBITORS | SYNNOVATION THERAPEUTICS, INC. (US) | 2023-06-29 | — | — | WO | disclosed |