⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25697286 | 1.00 | — | — | |
| SCHEMBL25697284 | 0.91 | LMNA (0.30) | — | |
| SCHEMBL25697342 | 0.91 | LMNA (0.30) | — | |
| SCHEMBL25697341 | 0.91 | LMNA (0.30) | — | |
| SCHEMBL25697316 | 0.87 | — | — | |
| SCHEMBL25697314 | 0.87 | — | — | |
| SCHEMBL25697290 | 0.85 | — | — | |
| SCHEMBL25696653 | 0.85 | — | — | |
| SCHEMBL25697289 | 0.85 | — | — | |
| SCHEMBL19969391 | 0.81 | LMNA (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230203060-A1 | FUSED TRICYCLIC COMPOUND, PHARMACEUTICAL COMPOSITION THEREOF, AND USE THEREOF | GENFLEET THERAPEUTICS (SHANGHAI) INC. (CN) | 2023-06-29 | — | — | US | disclosed |
| US-20230203060-A1 | FUSED TRICYCLIC COMPOUND, PHARMACEUTICAL COMPOSITION THEREOF, AND USE THEREOF | GENFLEET THERAPEUTICS (SHANGHAI) INC. (CN) | 2023-06-29 | — | — | US | disclosed |