⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12371954 | 0.85 | LMNA (0.31) | — | |
| SCHEMBL12903081 | 0.85 | LMNA (0.31) | — | |
| SCHEMBL12371724 | 0.85 | LMNA (0.31) | — | |
| SCHEMBL24410794 | 0.79 | — | — | |
| SCHEMBL24410795 | 0.79 | — | — | |
| SCHEMBL24966316 | 0.73 | — | — | |
| SCHEMBL22062797 | 0.73 | — | — | |
| SCHEMBL24735051 | 0.72 | — | — | |
| SCHEMBL12312746 | 0.71 | LMNA (0.31) | — | |
| SCHEMBL24625325 | 0.71 | LMNA (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230203060-A1 | FUSED TRICYCLIC COMPOUND, PHARMACEUTICAL COMPOSITION THEREOF, AND USE THEREOF | GENFLEET THERAPEUTICS (SHANGHAI) INC. (CN) | 2023-06-29 | — | — | US | disclosed |
| US-20230203060-A1 | FUSED TRICYCLIC COMPOUND, PHARMACEUTICAL COMPOSITION THEREOF, AND USE THEREOF | GENFLEET THERAPEUTICS (SHANGHAI) INC. (CN) | 2023-06-29 | — | — | US | disclosed |