Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4A | O75164 | 3/20 | 0.80 |
| ▸ | KDM6B | O15054 | 1/20 | 0.80 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.80 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.80 |
| ▸ | KDM5A | P29375 | 1/20 | 0.80 |
| ▸ | BLVRB | P30043 | 1/20 | 0.80 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.80 |
| ▸ | KCND3 | Q9UK17 | 1/20 | 0.80 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Deferasirox SCHEMBL29381781 | 0.89 | KDM4A (1.00) | KDM4AKDM6BABCC4ABCB11KDM5A | |
| Deferasirox SCHEMBL61756 | 0.89 | KDM4A (1.00) | KDM4AKDM6BABCC4ABCB11KDM5A | |
| SCHEMBL5843740 | 0.84 | KDM4A (0.85) | KDM4AKDM6BABCC4ABCB11KDM5A | |
| SCHEMBL5843247 | 0.82 | KDM4A (0.81) | KDM4AKDM6BABCC4ABCB11KDM5A | |
| SCHEMBL20080980 | 0.82 | KDM4A (0.85) | KDM4AKDM6BABCC4ABCB11KDM5A | |
| SCHEMBL22184113 | 0.81 | KDM4A (0.80) | KDM4AKDM6BABCC4ABCB11KDM5A | |
| SCHEMBL19722958 | 0.81 | KDM4A (0.78) | KDM4AKDM6BABCC4ABCB11KDM5A | |
| SCHEMBL5842285 | 0.80 | KDM4A (0.81) | KDM4AKDM6BABCC4ABCB11KDM5A | |
| SCHEMBL20620461 | 0.79 | KDM4A (0.80) | KDM4AKDM6BABCC4ABCB11KDM5A | |
| SCHEMBL21232846 | 0.79 | KDM4A (0.76) | KDM4AKDM6BABCC4ABCB11KDM5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2964202-B2 | ORAL FORMULATIONS OF DEFERASIROX | NOVARTIS AG (CH) | 2023-05-31 | — | — | EP | disclosed |