Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4A | O75164 | 3/20 | 1.00 |
| ▸ | KDM6B | O15054 | 1/20 | 1.00 |
| ▸ | ABCC4 | O15439 | 1/20 | 1.00 |
| ▸ | ABCB11 | O95342 | 1/20 | 1.00 |
| ▸ | KDM5A | P29375 | 1/20 | 1.00 |
| ▸ | BLVRB | P30043 | 1/20 | 1.00 |
| ▸ | SCN5A | Q14524 | 1/20 | 1.00 |
| ▸ | KCND3 | Q9UK17 | 1/20 | 1.00 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Deferasirox SCHEMBL29381781 | 1.00 | KDM4A (1.00) | KDM4AKDM6BABCC4ABCB11KDM5A | |
| SCHEMBL5843740 | 0.92 | KDM4A (0.85) | KDM4AKDM6BABCC4ABCB11KDM5A | |
| SCHEMBL20080980 | 0.92 | KDM4A (0.85) | KDM4AKDM6BABCC4ABCB11KDM5A | |
| SCHEMBL5843247 | 0.90 | KDM4A (0.81) | KDM4AKDM6BABCC4ABCB11KDM5A | |
| SCHEMBL5842285 | 0.90 | KDM4A (0.81) | KDM4AKDM6BABCC4ABCB11KDM5A | |
| SCHEMBL22184113 | 0.89 | KDM4A (0.80) | KDM4AKDM6BABCC4ABCB11KDM5A | |
| SCHEMBL20620461 | 0.89 | KDM4A (0.80) | KDM4AKDM6BABCC4ABCB11KDM5A | |
| SCHEMBL25697702 | 0.89 | KDM4A (0.80) | KDM4AKDM6BABCC4ABCB11KDM5A | |
| SCHEMBL4370368 | 0.88 | KDM4A (1.00) | KDM4AKDM6BABCC4ABCB11KDM5A | |
| SCHEMBL19722958 | 0.88 | KDM4A (0.78) | KDM4AKDM6BABCC4ABCB11KDM5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1998 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4739300-A1 | MODULATORS OF IRON METABOLISM FOR TREATING CONDITIONS ASSOCIATED WITH CONE PHOTORECEPTOR DEGENERATION | SORBONNE UNIVERSITE (FR) | 2026-05-13 | — | — | EP | claimed |
| EP-3310354-B1 | IMPROVED FORMULATIONS OF DEFERASIROX AND METHODS OF MAKING THE SAME | AUSTINPX LLC (US) | 2026-02-25 | — | — | EP | claimed |
| US-12544406-B2 | Induced pluripotent stem cell derived glial enriched progenitor cells for the treatment of white matter stroke | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2026-02-10 | — | — | US | claimed |
| US-20250388791-A1 | CYCLIC ACETAL CROSSLINKER AND SOLVENT FOR FORMALDEHYDE RESIN | HEXION INC. (US) | 2025-12-25 | — | — | US | claimed |
| US-20250275946-A1 | COMBINATION THERAPY FOR THE TREATMENT OF CANCER | UNM RAINFOREST INNOVATIONS (US) | 2025-09-04 | — | — | US | claimed |
| US-20250221415-A1 | Materials and Methods for Treating Iron Deficiencies and Iron Chlorosis in Plants | LOCUS SOLUTIONS IPCO, LLC | 2025-07-10 | — | — | US | claimed |
| US-20250194641-A1 | Materials and Methods for Iron Capture and Greenhouse Gas Reduction | LOCUS SOLUTIONS IPCO, LLC | 2025-06-19 | — | — | US | claimed |
| US-20250187058-A1 | Materials and Methods for Remediating and Mitigating Iron Pollution | LOCUS SOLUTIONS IPCO, LLC | 2025-06-12 | — | — | US | claimed |
| US-20250176557-A1 | Materials and Methods for Control of Iron-Capturing Pathogens | LOCUS SOLUTIONS IPCO, LLC | 2025-06-05 | — | — | US | claimed |
| EP-4551341-A1 | MATERIALS AND METHODS FOR REMEDIATING AND MITIGATING IRON POLLUTION | Locus Solutions IPCO, LLC (US) | 2025-05-14 | — | — | EP | claimed |
| WO-2005058320-A1 | COMBINATION OF (a) N-{5-[4-(4-METHYL-PIPERAZINO-METHYL)-BENZOYLAMIDO]-2METHYLPHENYL}-4-(3-PYRIDYL)-2-PYRIMIDINE-AMINE AND (b) AT LEAST ONE HYPUSINATION INHIBITOR AND THE USE THEREOF | NOVARTIS AG (CH) | 2005-06-30 | — | — | WO | claimed |
| JP-3541042-B2 | — | — | 2004-07-07 | — | — | JP | claimed |
| US-20030203954-A1 | Substituted 3, 5-diphenyl-1,2,4-triazoles and their use as pharmaceutical metal chelators | LATTMANN RENE (CH) | 2003-10-30 | — | — | US | claimed |
| US-6596750-B2 | Compounds have useful pharmaceutical properties and are particularly active as iron chelators. They can be used for the treatment of iron overload in warm-blooded animals. | NOVARTIS AG (CH) | 2003-07-22 | — | — | US | claimed |
| US-20030069273-A1 | Substituted 3,5-diphenyl-1,2,4-triazoles and their use as pharmaceutical metal chelators | LATTMANN RENE (CH) | 2003-04-10 | — | — | US | claimed |
| EP-0914118-B1 | SUBSTITUTED 3,5-DIPHENYL-1,2,4-TRIAZOLES AND THEIR USE AS PHARMACEUTICAL METAL CHELATORS | NOVARTIS AG (CH) | 2002-10-23 | — | — | EP | claimed |
| US-6465504-B1 | Substituted 3,5-diphenyl-1,2,4-triazoles and their use as pharmaceutical metal chelators | NOVARTIS AG (CH) | 2002-10-15 | — | — | US | claimed |
| JP-2000507601-A | — | — | 2000-06-20 | — | — | JP | claimed |
| EP-0914118-A1 | SUBSTITUTED 3,5-DIPHENYL-1,2,4-TRIAZOLES AND THEIR USE AS PHARMACEUTICAL METAL CHELATORS | Novartis AG (CH) | 1999-05-12 | — | — | EP | claimed |
| WO-1997049395-A1 | SUBSTITUTED 3,5-DIPHENYL-1,2,4-TRIAZOLES AND THEIR USE AS PHARMACEUTICAL METAL CHELATORS | NOVARTIS-ERFINDUNGEN VERWALTUNGSGESELLSCHAFT M.B.H. (AT) | 1997-12-31 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030069273-A1 | Substituted 3,5-diphenyl-1,2,4-triazoles and their use as pharmaceutical metal chelators | TFRC, SLC40A1, FECH | KDM4A 2799/4885KDM6B 2804/4885ABCC4 679/4885 |
| US-12544406-B2 | Induced pluripotent stem cell derived glial enriched progenitor cells for the treatment of white matter stroke | GFRA3, NES, DCX | KDM4A 2939/4885KDM6B 1823/4885ABCC4 1755/4885 |
| US-20250388791-A1 | CYCLIC ACETAL CROSSLINKER AND SOLVENT FOR FORMALDEHYDE RESIN | SMCHD1, FGB, UFL1 | KDM4A 304/4885KDM6B 287/4885ABCC4 2471/4885 |
| US-20030203954-A1 | Substituted 3, 5-diphenyl-1,2,4-triazoles and their use as pharmaceutical metal chelators | TFRC, SLC40A1, FECH | KDM4A 2799/4885KDM6B 2804/4885ABCC4 679/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.