SCHEMBL256986

SCHEMBL256986

CC1CN=CN1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19346128 1.00
SCHEMBL10296481 0.72
SCHEMBL13536482 0.69 GABRA1 (0.32)
SCHEMBL22102879 0.65
SCHEMBL21301342 0.63
SCHEMBL19708801 0.61
SCHEMBL24222556 0.61
SCHEMBL20334261 0.61
SCHEMBL10296487 0.61
SCHEMBL19670762 0.61

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 121 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240067611-A1 PHENYL CYCLOHEXANONE DERIVATIVES AND METHODS OF MAKING AND USING THEM SPIRIFY PHARMA INC. 2024-02-29 US disclosed
US-11827606-B2 Phenyl cyclohexanone derivatives and methods of making and using them SPIRIFY PHARMA INC. (US) 2023-11-28 US disclosed
EP-4175820-A1 COATINGS FROM POLYISOCYANURATE COATINGS (RIM) AND THEIR USE IN INJECTION MOLDING PROCESSES Covestro Deutschland AG (DE) 2023-05-10 EP disclosed
WO-2023066292-A1 TRICYCLIC BORONIC ACID DERIVATIVE, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF 上海济煜医药科技有限公司 2023-04-27 WO disclosed
WO-2022119756-A9 COMPOSITIONS AND METHODS FOR INHIBITING M PRO PROTEASE ACTIVITY AND FOR PREVENTING AND TREATING SARS-COV-2 INFECTION ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) 2023-04-27 WO disclosed
US-11548984-B2 Light- or heat-curing method and curable resin composition FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) 2023-01-10 US disclosed
CN-110678500-B Photo-or thermosetting method and curable resin composition 富士胶片和光纯药株式会社 2022-10-14 CN disclosed
WO-2022119756-A1 COMPOSITIONS AND METHODS FOR INHIBITING M PRO PROTEASE ACTIVITY AND FOR PREVENTING AND TREATING SARS-COV-2 INFECTION ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) 2022-06-09 WO disclosed
US-20220145339-A1 METHOD FOR PREPARATION OF PRIMARY AMINE COMPOUNDS MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (DE) 2022-05-12 US disclosed
EP-3956390-A1 METHOD FOR SURFACE FUNCTIONALISATION IN A SUPERCRITICAL FLUID MEDIUM Commissariat à l'Energie Atomique et aux Energies Alternatives (FR) 2022-02-23 EP disclosed
WO-2007060028-A1 NAPTHYRIDINE COMPOUNDS AS ROCK INHIBITORS GPC BIOTECH AG (DE) 2007-05-31 WO disclosed
US-20070049495-A1 Ethylene derivatives and pesticides containing said derivatives NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2007-03-01 US disclosed
EP-1757607-A1 N5-substituted benzo¬2,3|azepino¬4,5-b|indol-6-ones for treating tropical diseases Molisa GmbH (DE) 2007-02-28 EP disclosed
EP-1557165-A1 COMBINATION DRUG Eisai Co., Ltd. (JP) 2005-07-27 EP disclosed
WO-2005023818-A2 HETEROBICYCLIC COMPOUNDS AS PHARMACEUTICALLY ACTIVE AGENTS GPC BIOTECH AG (DE) 2005-03-17 WO disclosed
EP-1514552-A1 NOVEL FUSED IMIDAZOLE DERIVATIVE Eisai Co., Ltd. (JP) 2005-03-16 EP disclosed
US-20040116328-A1 Condensed imidazole derivatives EISAI CO., LTD. (JP) 2004-06-17 US disclosed
CN-1257864-A Imidazoline compound, preparing process thereof and pharmaceutical composition contg. same ADIR (FR) 2000-06-28 CN disclosed
US-4209583-A AMIDINE COMPOUND AGFA-GEVAERT, A.G. (DE) 1980-06-24 US disclosed
US-4094811-A REDUCING SILVER SALTS IN THE PRESENCE OF A HETEROCYCLIC 5- OR 6-MEMBERED NITROGEN COMPOUND AGFA-GEVAERT AKTIENGESELLSCHAFT (DT) 1978-06-13 US disclosed