Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B10 | O60218 | 6/20 | 0.55 |
| ▸ | AKR1B1 | P15121 | 6/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25699257 | 0.92 | AKR1B10 (0.52) | AKR1B10AKR1B1ALDH1A1LMNAKMT2A | |
| SCHEMBL5710793 | 0.89 | AKR1B10 (0.67) | AKR1B10AKR1B1ALDH1A1LMNAKMT2A | |
| SCHEMBL15929682 | 0.87 | AKR1B10 (0.65) | AKR1B10AKR1B1ALDH1A1LMNAKMT2A | |
| SCHEMBL14582393 | 0.83 | AKR1B10 (0.60) | AKR1B10AKR1B1ALDH1A1LMNAKMT2A | |
| Phenol SCHEMBL8680168 | 0.83 | AKR1B10 (0.62) | AKR1B10AKR1B1ALDH1A1LMNAKMT2A | |
| SCHEMBL22881929 | 0.81 | AKR1B10 (0.61) | AKR1B10AKR1B1ALDH1A1LMNAKMT2A | |
| SCHEMBL25177109 | 0.78 | AKR1B10 (0.53) | AKR1B10AKR1B1ALDH1A1LMNAKMT2A | |
| SCHEMBL25177110 | 0.78 | AKR1B10 (0.53) | AKR1B10AKR1B1ALDH1A1LMNAKMT2A | |
| SCHEMBL19279512 | 0.78 | AKR1B10 (0.83) | AKR1B10AKR1B1ALDH1A1LMNAKMT2A | |
| SCHEMBL9277968 | 0.78 | AKR1B10 (0.83) | AKR1B10AKR1B1ALDH1A1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023081840-A1 | KRAS G12C INHIBITORS | FRONTIER MEDICINES CORPORATION (US) | 2023-05-11 | — | — | WO | disclosed |