Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | MAOA | P21397 | 3/20 | 0.39 |
| ▸ | MAOB | P27338 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9681661 | 0.84 | NPC1 (0.55) | NOTUMKDM4EALDH1A1RAB9ACA1 | |
| SCHEMBL22862410 | 0.83 | RAB9A (0.60) | NOTUMKDM4EALDH1A1RAB9ACA1 | |
| SCHEMBL28798361 | 0.83 | NOTUM (0.52) | NOTUMKDM4EALDH1A1RAB9ACA2 | |
| SCHEMBL7829176 | 0.83 | RAB9A (0.60) | NOTUMKDM4EALDH1A1RAB9AMAOA | |
| SCHEMBL8590849 | 0.83 | KDM4E (0.60) | NOTUMKDM4EALDH1A1RAB9AGSK3B | |
| SCHEMBL23734594 | 0.83 | NOTUM (0.52) | NOTUMKDM4EALDH1A1RAB9AGSK3B | |
| SCHEMBL408280 | 0.82 | RAB9A (0.57) | NOTUMKDM4EALDH1A1RAB9AGSK3B | |
| SCHEMBL25955062 | 0.82 | NOTUM (0.49) | NOTUMKDM4EALDH1A1RAB9AGSK3B | |
| SCHEMBL19173086 | 0.80 | NOTUM (0.50) | NOTUMKDM4EALDH1A1RAB9AGSK3B | |
| SCHEMBL18177029 | 0.80 | KDM4E (0.57) | NOTUMKDM4EALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023109965-A1 | CAMPTOTHECIN COMPOUND AND CONJUGATE THEREOF | 迈威(上海)生物科技股份有限公司 | 2023-06-22 | — | — | WO | disclosed |