Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 4/20 | 0.43 |
| ▸ | CES2 | O00748 | 2/20 | 0.42 |
| ▸ | CES1 | P23141 | 2/20 | 0.42 |
| ▸ | PDE2A | O00408 | 2/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | ACP3 | P15309 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.39 |
| ▸ | HTR3B | O95264 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.39 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.39 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.38 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.38 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.38 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1052004 | 1.00 | KIF11 (0.43) | KIF11CES2CES1PDE2ATAAR1 | |
| SCHEMBL296390 | 1.00 | KIF11 (0.43) | KIF11CES2CES1PDE2ATAAR1 | |
| Hydrochloric Acid SCHEMBL25210776 | 0.98 | KIF11 (0.41) | KIF11CES2CES1PDE2ATAAR1 | |
| Hydrochloric Acid SCHEMBL25244098 | 0.98 | KIF11 (0.41) | KIF11CES2CES1PDE2ATAAR1 | |
| Hydrochloric Acid SCHEMBL18247977 | 0.82 | PDE2A (0.47) | KIF11CES2CES1PDE2ATAAR1 | |
| Hydrochloric Acid SCHEMBL20494402 | 0.82 | PDE2A (0.47) | KIF11CES2CES1PDE2ATAAR1 | |
| SCHEMBL15137434 | 0.80 | KIF11 (0.46) | KIF11CES2CES1PDE2ATAAR1 | |
| SCHEMBL28471171 | 0.80 | KIF11 (0.46) | KIF11CES2CES1PDE2ATAAR1 | |
| SCHEMBL15670412 | 0.80 | KIF11 (0.46) | KIF11CES2CES1PDE2ATAAR1 | |
| SCHEMBL2009543 | 0.80 | KIF11 (0.46) | KIF11CES2CES1PDE2ATAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023094830-A1 | SULFONAMIDE COMPOUNDS FOR THE TREATMENT OF NEUROLOGICAL CONDITIONS | LARIO THERAPEUTICS LIMITED (GB) | 2023-06-01 | — | — | WO | disclosed |