Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 5/20 | 0.62 |
| ▸ | CYP11B1 | P15538 | 5/20 | 0.62 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.62 |
| ▸ | MAOB | P27338 | 2/20 | 0.57 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.51 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.51 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.50 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.49 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.49 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.49 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.49 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.46 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.46 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.45 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.45 |
| ▸ | RXRA | P19793 | 2/20 | 0.44 |
| ▸ | RXRB | P28702 | 2/20 | 0.44 |
| ▸ | RXRG | P48443 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6061899 | 0.87 | CYP19A1 (0.53) | CYP19A1CYP11B1CYP11B2MAOBPTGDR2 | |
| SCHEMBL70797 | 0.81 | MAOB (0.60) | CYP19A1CYP11B1CYP11B2MAOBGABRG2 | |
| SCHEMBL2567774 | 0.81 | CYP19A1 (0.53) | CYP19A1CYP11B1CYP11B2MAOBPTGER1 | |
| SCHEMBL6477203 | 0.81 | MAOB (0.55) | CYP19A1CYP11B1CYP11B2MAOBPTGDR2 | |
| SCHEMBL9213631 | 0.81 | CYP11B1 (0.61) | CYP19A1CYP11B1CYP11B2MAOBPTGDR2 | |
| SCHEMBL2572668 | 0.81 | CYP19A1 (0.61) | CYP19A1CYP11B1CYP11B2MAOBPTGDR2 | |
| SCHEMBL6509372 | 0.80 | CHEK2 (0.50) | CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL20302267 | 0.80 | MAOB (0.58) | CYP19A1CYP11B1CYP11B2MAOBPTGER1 | |
| SCHEMBL6431004 | 0.80 | MAOB (0.58) | CYP19A1CYP11B1CYP11B2MAOBPTGER1 | |
| SCHEMBL6072398 | 0.80 | MAOB (0.58) | CYP19A1CYP11B1CYP11B2MAOBPTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1813623-B1 | PURINENUCLEOSIDE DERIVATIVE MODIFIED IN 8-POSITION AND MEDICINAL USE THEREOF | KISSEI PHARMACEUTICAL (JP) | 2011-11-09 | — | — | EP | disclosed |
| US-20100249054-A9 | PURINE NUCLEOSIDE DERIVATIVE MODIFIED IN 8-POSITION AND MEDICAL USE THEREOF | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2010-09-30 | — | — | US | disclosed |
| US-7795236-B2 | Purine nucleoside derivative modified in 8-position and medical use thereof | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2010-09-14 | — | — | US | disclosed |
| US-20070179115-A1 | Purinenucleoside derivative modified in 8-position and medical use thereof | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2007-08-02 | — | — | US | disclosed |
| EP-1813623-A1 | PURINENUCLEOSIDE DERIVATIVE MODIFIED IN 8-POSITION AND MEDICINAL USE THEREOF | Kissei Pharmaceutical Co., Ltd. (JP) | 2007-08-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100249054-A9 | PURINE NUCLEOSIDE DERIVATIVE MODIFIED IN 8-POSITION AND MEDICAL USE THEREOF | NUDT1, PNP, SLC28A2 | CYP19A1 4432/4885CYP11B1 1018/4885CYP11B2 957/4885 |
| US-20070179115-A1 | Purinenucleoside derivative modified in 8-position and medical use thereof | NUDT1, SLC28A2, PNP | CYP19A1 4354/4885CYP11B1 864/4885CYP11B2 754/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.